Cap Z(36/32), a barbed end actin-capping protein, is a component of the Z-line of skeletal muscle

doi:10.1083/jcb.105.1.371

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Cap Z(36/32), a barbed end actin-capping protein, is a component of the Z-line of skeletal muscle

JF Casella, SW Craig, DJ Maack and AE Brown

Various biological activities have been attributed to actin-capping proteins based on their in vitro effects on actin filaments. However, there is little direct evidence for their in vivo activities. In this paper, we show that Cap Z(36/32), a barbed end, actin-capping protein isolated from muscle (Casella, J. F., D. J. Maack, and S. Lin, 1986, J. Biol. Chem., 261:10915-10921) is localized to the barbed ends of actin filaments by electron microscopy and to the Z-line of chicken skeletal muscle by indirect immunofluorescence and electron microscopy. Since actin filaments associate with the Z-line at their barbed ends, these findings suggest that Cap Z(36/32) may play a role in regulating length, orienting, or attaching actin filaments to Z-discs.
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Schafer, D. A., Welch, M. D., Machesky, L. M., Bridgman, P. C., Meyer, S. M., Cooper, J. A. (1998). Visualization and Molecular Analysis of Actin Assembly in Living Cells. JCB 143: 1919-1930 [Abstract] [Full Text]
Chen, J., Akyurek, L. M., Fellstrom, B., Hayry, P., Paul, L. C. (1998). Eotaxin and Capping Protein in Experimental Vasculopathy. Am. J. Pathol. 153: 81-90 [Abstract] [Full Text]
Wang, B., Golemis, E. A., Kruh, G. D. (1997). ArgBP2, a Multiple Src Homology 3�Domain-containing, Arg/Abl-interacting Protein, Is Phosphorylated in v-Abl-transformed Cells and Localized in Stress Fibers and Cardiocyte Z-disks. J. Biol. Chem. 272: 17542-17550 [Abstract] [Full Text]
Wang, K., Knipfer, M., Huang, Q.-Q., van Heerden, A., Hsu, L. C.-L., Gutierrez, G., Quian, X.-L., Stedman, H. (1996). Human Skeletal Muscle Nebulin Sequence Encodes a Blueprint for Thin Filament Architecture. J. Biol. Chem. 271: 4304-4314 [Abstract] [Full Text]
Ivanenkov, V. V., Jamieson, G. A. Jr., Gruenstein, E., Dimlich, R. V. W. (1995). Characterization of S-100b Binding Epitopes. J. Biol. Chem. 270: 14651-14658 [Abstract] [Full Text]
Terasaki, A., Nakagawa, H, Kotani, E, Mori, H, Ohashi, K (1995). A high molecular mass protein isolated from chicken gizzard: its localization at the dense plaques and dense bodies of smooth muscle and the Z-disks of skeletal muscle. J. Cell Sci. 108: 857-868 [Abstract]
Waddle, J., Cooper, J., Waterston, R. (1994). Transient localized accumulation of actin in Caenorhabditis elegans blastomeres with oriented asymmetric divisions. Development 120: 2317-2328 [Abstract]
Epstein, H., Fischman, D. (1991). Molecular analysis of protein assembly in muscle development. Science 251: 1039-1044 [Abstract]