Laura M. Macheskya and
Robert H. Insalla a Department of Biochemistry, University of Birmingham, Birmingham, B15 2TT, UK
Correspondence to:
Laura M. Machesky, Department of Biochemistry, University of Birmingham, Birmingham B15 2TT, UK. Tel: 44-121-414-2504., r.h.insall{at}bham.ac.uk (E-mail), 44-121-414-3982 (fax)
Delatour, V., Helfer, E., Didry, D., Le, K. H. D., Gaucher, J.-F., Carlier, M.-F., Romet-Lemonne, G.
(2008). Arp2/3 Controls the Motile Behavior of N-WASP-Functionalized GUVs and Modulates N-WASP Surface Distribution by Mediating Transient Links with Actin Filaments. Biophys. J
94: 4890-4905
[Abstract][Full Text]
Martinez-Heredia, J., de Mateo, S., Vidal-Taboada, J. M., Ballesca, J. L., Oliva, R.
(2008). Identification of proteomic differences in asthenozoospermic sperm samples. Hum Reprod
23: 783-791
[Abstract][Full Text]
Zhang, W., Gunst, S. J.
(2008). Interactions of Airway Smooth Muscle Cells with Their Tissue Matrix: Implications for Contraction. Proc Am Thorac Soc
5: 32-39
[Abstract][Full Text]
Llado, A., Timpson, P., Vila de Muga, S., Moreto, J., Pol, A., Grewal, T., Daly, R. J., Enrich, C., Tebar, F.
(2008). Protein Kinase C{delta} and Calmodulin Regulate Epidermal Growth Factor Receptor Recycling from Early Endosomes through Arp2/3 Complex and Cortactin. Mol. Biol. Cell
19: 17-29
[Abstract][Full Text]
Kraemer, A., Goodwin, M., Verma, S., Yap, A. S., Ali, R. G.
(2007). Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1. Am. J. Physiol. Cell Physiol.
292: C1061-C1069
[Abstract][Full Text]
Le Clainche, C., Schlaepfer, D., Ferrari, A., Klingauf, M., Grohmanova, K., Veligodskiy, A., Didry, D., Le, D., Egile, C., Carlier, M.-F., Kroschewski, R.
(2007). IQGAP1 Stimulates Actin Assembly through the N-Wasp-Arp2/3 Pathway. J. Biol. Chem.
282: 426-435
[Abstract][Full Text]
Wessels, D., Srikantha, T., Yi, S., Kuhl, S., Aravind, L., Soll, D. R.
(2006). The Shwachman-Bodian-Diamond syndrome gene encodes an RNA-binding protein that localizes to the pseudopod of Dictyostelium amoebae during chemotaxis. J. Cell Sci.
119: 370-379
[Abstract][Full Text]
Mingle, L. A., Okuhama, N. N., Shi, J., Singer, R. H., Condeelis, J., Liu, G.
(2005). Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. J. Cell Sci.
118: 2425-2433
[Abstract][Full Text]
van der Gucht, J., Paluch, E., Plastino, J., Sykes, C.
(2005). Stress release drives symmetry breaking for actin-based movement. Proc. Natl. Acad. Sci. USA
102: 7847-7852
[Abstract][Full Text]
Beaulieu, V., Da Silva, N., Pastor-Soler, N., Brown, C. R., Smith, P. J. S., Brown, D., Breton, S.
(2005). Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H+-ATPase Recycling. J. Biol. Chem.
280: 8452-8463
[Abstract][Full Text]
Govek, E.-E., Newey, S. E., Van Aelst, L.
(2005). The role of the Rho GTPases in neuronal development. Genes Dev.
19: 1-49
[Abstract][Full Text]
Birukov, K. G., Bochkov, V. N., Birukova, A. A., Kawkitinarong, K., Rios, A., Leitner, A., Verin, A. D., Bokoch, G. M., Leitinger, N., Garcia, Joe. G.N.
(2004). Epoxycyclopentenone-Containing Oxidized Phospholipids Restore Endothelial Barrier Function via Cdc42 and Rac. Circ. Res.
95: 892-901
[Abstract][Full Text]
Watanabe, H., Yokozeki, T., Yamazaki, M., Miyazaki, H., Sasaki, T., Maehama, T., Itoh, K., Frohman, M. A., Kanaho, Y.
(2004). Essential Role for Phospholipase D2 Activation Downstream of ERK MAP Kinase in Nerve Growth Factor-stimulated Neurite Outgrowth from PC12 Cells. J. Biol. Chem.
279: 37870-37877
[Abstract][Full Text]
Calle, Y., Jones, G. E., Jagger, C., Fuller, K., Blundell, M. P., Chow, J., Chambers, T., Thrasher, A. J.
(2004). WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption. Blood
103: 3552-3561
[Abstract][Full Text]
Etienne-Manneville, S.
(2004). Cdc42 - the centre of polarity. J. Cell Sci.
117: 1291-1300
[Abstract][Full Text]
Helwani, F. M., Kovacs, E. M., Paterson, A. D., Verma, S., Ali, R. G., Fanning, A. S., Weed, S. A., Yap, A. S.
(2004). Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization. J. Cell Biol.
164: 899-910
[Abstract][Full Text]
Arora, P. D., Glogauer, M., Kapus, A., Kwiatkowski, D. J., McCulloch, C. A.
(2004). Gelsolin Mediates Collagen Phagocytosis through a Rac-dependent Step. Mol. Biol. Cell
15: 588-599
[Abstract][Full Text]
Kjeken, R., Egeberg, M., Habermann, A., Kuehnel, M., Peyron, P., Floetenmeyer, M., Walther, P., Jahraus, A., Defacque, H., Kuznetsov, S. A., Griffiths, G.
(2004). Fusion between Phagosomes, Early and Late Endosomes: A Role for Actin in Fusion between Late, but Not Early Endocytic Organelles. Mol. Biol. Cell
15: 345-358
[Abstract][Full Text]
da Costa, S. R., Sou, E., Xie, J., Yarber, F. A., Okamoto, C. T., Pidgeon, M., Kessels, M. M., Mircheff, A. K., Schechter, J. E., Qualmann, B., Hamm-Alvarez, S. F.
(2003). Impairing Actin Filament or Syndapin Functions Promotes Accumulation of Clathrin-coated Vesicles at the Apical Plasma Membrane of Acinar Epithelial Cells. Mol. Biol. Cell
14: 4397-4413
[Abstract][Full Text]
Merlot, S., Firtel, R. A.
(2003). Leading the way: directional sensing through phosphatidylinositol 3-kinase and other signaling pathways. J. Cell Sci.
116: 3471-3478
[Abstract][Full Text]
Gunst, S. J., Fredberg, J. J.
(2003). The first three minutes: smooth muscle contraction, cytoskeletal events, and soft glasses. J. Appl. Physiol.
95: 413-425
[Abstract][Full Text]
Carnegie, G. K., Scott, J. D.
(2003). A-kinase anchoring proteins and neuronal signaling mechanisms. Genes Dev.
17: 1557-1568
[Full Text]
Papakonstanti, E. A., Kampa, M., Castanas, E., Stournaras, C.
(2003). A Rapid, Nongenomic, Signaling Pathway Regulates the Actin Reorganization Induced by Activation of Membrane Testosterone Receptors. Mol. Endocrinol.
17: 870-881
[Abstract][Full Text]
Okabe, T., Nakamura, T., Nishimura, Y. N., Kohu, K., Ohwada, S., Morishita, Y., Akiyama, T.
(2003). RICS, a Novel GTPase-activating Protein for Cdc42 and Rac1, Is Involved in the beta -Catenin-N-cadherin and N-Methyl-D-aspartate Receptor Signaling. J. Biol. Chem.
278: 9920-9927
[Abstract][Full Text]
Soderling, S. H., Langeberg, L. K., Soderling, J. A., Davee, S. M., Simerly, R., Raber, J., Scott, J. D.
(2003). Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice. Proc. Natl. Acad. Sci. USA
100: 1723-1728
[Abstract][Full Text]
Magdalena, J., Millard, T. H., Machesky, L. M.
(2003). Microtubule involvement in NIH 3T3 Golgi and MTOC polarity establishment. J. Cell Sci.
116: 743-756
[Abstract][Full Text]
Magdalena, J., Millard, T. H., Etienne-Manneville, S., Launay, S., Warwick, H. K., Machesky, L. M.
(2003). Involvement of the Arp2/3 Complex and Scar2 in Golgi Polarity in Scratch Wound Models. Mol. Biol. Cell
14: 670-684
[Abstract][Full Text]
Samstag, Y., Eibert, S. M., Klemke, M., Wabnitz, G. H.
(2003). Actin cytoskeletal dynamics in T lymphocyte activation and migration. J. Leukoc. Biol.
73: 30-48
[Abstract][Full Text]
Strege, P. R., Holm, A. N., Rich, A., Miller, S. M., Ou, Y., Sarr, M. G., Farrugia, G.
(2003). Cytoskeletal modulation of sodium current in human jejunal circular smooth muscle cells. Am. J. Physiol. Cell Physiol.
284: C60-C66
[Abstract][Full Text]
Zeng, H., Zhao, D., Mukhopadhyay, D.
(2002). KDR Stimulates Endothelial Cell Migration through Heterotrimeric G Protein Gq/11-mediated Activation of a Small GTPase RhoA. J. Biol. Chem.
277: 46791-46798
[Abstract][Full Text]
Soulard, A., Lechler, T., Spiridonov, V., Shevchenko, A., Shevchenko, A., Li, R., Winsor, B.
(2002). Saccharomyces cerevisiae Bzz1p Is Implicated with Type I Myosins in Actin Patch Polarization and Is Able To Recruit Actin-Polymerizing Machinery In Vitro. Mol. Cell. Biol.
22: 7889-7906
[Abstract][Full Text]
Copeland, J. W., Treisman, R.
(2002). The Diaphanous-related Formin mDia1 Controls Serum Response Factor Activity through its Effects on Actin Polymerization. Mol. Biol. Cell
13: 4088-4099
[Abstract][Full Text]
Mogilner, A., Edelstein-Keshet, L.
(2002). Regulation of Actin Dynamics in Rapidly Moving Cells: A Quantitative Analysis. Biophys. J
83: 1237-1258
[Abstract][Full Text]
Kanzaki, M., Watson, R. T., Hou, J. C., Stamnes, M., Saltiel, A. R., Pessin, J. E.
(2002). Small GTP-binding Protein TC10 Differentially Regulates Two Distinct Populations of Filamentous Actin in 3T3L1 Adipocytes. Mol. Biol. Cell
13: 2334-2346
[Abstract][Full Text]
Doevendans, P. A., van Eys, G.
(2002). Smooth muscle cells on the move: the battle for actin. Cardiovasc Res
54: 499-502
[Full Text]
Van Aelst, L., Symons, M.
(2002). Role of Rho family GTPases in epithelial morphogenesis. Genes Dev.
16: 1032-1054
[Full Text]
Oberholzer, U., Marcil, A., Leberer, E., Thomas, D. Y., Whiteway, M.
(2002). Myosin I Is Required for Hypha Formation in Candidaalbicans. Eukaryot Cell
1: 213-228
[Abstract][Full Text]
Diakonova, M., Gunter, D. R., Herrington, J., Carter-Su, C.
(2002). SH2-Bbeta Is a Rac-binding Protein That Regulates Cell Motility. J. Biol. Chem.
277: 10669-10677
[Abstract][Full Text]
Zeng, H., Zhao, D., Mukhopadhyay, D.
(2002). Flt-1-mediated Down-regulation of Endothelial Cell Proliferation through Pertussis Toxin-sensitive G Proteins, beta gamma Subunits, Small GTPase CDC42, and Partly by Rac-1. J. Biol. Chem.
277: 4003-4009
[Abstract][Full Text]
Vetterkind, S., Miki, H., Takenawa, T., Klawitz, I., Scheidtmann, K.-H., Preuss, U.
(2002). The Rat Homologue of Wiskott-Aldrich Syndrome Protein (WASP)-interacting Protein (WIP) Associates with Actin Filaments, Recruits N-WASP from the Nucleus, and Mediates Mobilization of Actin from Stress Fibers in Favor of Filopodia Formation. J. Biol. Chem.
277: 87-95
[Abstract][Full Text]
Patel, K. G., Liu, C., Cameron, P. L., Cameron, R. S.
(2001). Myr 8, A Novel Unconventional Myosin Expressed during Brain Development Associates with the Protein Phosphatase Catalytic Subunits 1{alpha} and 1{gamma}1. J. Neurosci.
21: 7954-7968
[Abstract][Full Text]
Baluska, F., von Witsch, M., Peters, M., Hlavacka, A., Volkmann, D.
(2001). Mastoparan Alters Subcellular Distribution of Profilin and Remodels F-Actin Cytoskeleton in Cells of Maize Root Apices. Plant Cell Physiol
42: 912-922
[Abstract][Full Text]
Jung, G., Remmert, K., Wu, X., Volosky, J. M., III, J. A. H.
(2001). The Dictyostelium CARMIL Protein Links Capping Protein and the Arp2/3 Complex to Type I Myosins through Their SH3 Domains. J. Cell Biol.
153: 1479-1498
[Abstract][Full Text]
Leverrier, Y., Lorenzi, R., Blundell, M. P., Brickell, P., Kinnon, C., Ridley, A. J., Thrasher, A. J.
(2001). Cutting Edge: The Wiskott-Aldrich Syndrome Protein Is Required for Efficient Phagocytosis of Apoptotic Cells. J. Immunol.
166: 4831-4834
[Abstract][Full Text]
Stinchcombe, J. C., Barral, D. C., Mules, E. H., Booth, S., Hume, A. N., Machesky, L. M., Seabra, M. C., Griffiths, G. M.
(2001). Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes. J. Cell Biol.
152: 825-834
[Abstract][Full Text]
May, R., Machesky, L.
(2001). Phagocytosis and the actin cytoskeleton. J. Cell Sci.
114: 1061-1077
[Abstract]
Takai, Y., Sasaki, T., Matozaki, T.
(2001). Small GTP-Binding Proteins. Physiol. Rev.
81: 153-208
[Abstract][Full Text]
Jahraus, A., Egeberg, M., Hinner, B., Habermann, A., Sackman, E., Pralle, A., Faulstich, H., Rybin, V., Defacque, H., Griffiths, G.
(2001). ATP-dependent Membrane Assembly of F-Actin Facilitates Membrane Fusion. Mol. Biol. Cell
12: 155-170
[Abstract][Full Text]
Yamaguchi, H., Miki, H., Suetsugu, S., Ma, L., Kirschner, M. W., Takenawa, T.
(2000). Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP. Proc. Natl. Acad. Sci. USA
10.1073/pnas.190351397v1
[Abstract][Full Text]
Jimenez, C., Portela, R. A., Mellado, M., Rodriguez-Frade, J. M., Collard, J., Serrano, A., Martinez-A, C., Avila, J., Carrera, A. C.
(2000). Role of the PI3K Regulatory Subunit in the Control of Actin Organization and Cell Migration. J. Cell Biol.
151: 249-262
[Abstract][Full Text]
Rohatgi, R., Ho, H.-y. H., Kirschner, M. W.
(2000). Mechanism of N-WASP Activation by CDC42 and Phosphatidylinositol 4,5-bisphosphate. J. Cell Biol.
150: 1299-1310
[Abstract][Full Text]
Glogauer, M., Hartwig, J., Stossel, T.
(2000). Two Pathways Through Cdc42 Couple the N-formyl Receptor to Actin Nucleation in Permeabilized Human Neutrophils. J. Cell Biol.
150: 785-796
[Abstract][Full Text]
Skoble, J., Portnoy, D. A., Welch, M. D.
(2000). Three Regions within ActA Promote Arp2/3 Complex-mediated Actin Nucleation and Listeria monocytogenes Motility. J. Cell Biol.
150: 527-538
[Abstract][Full Text]
Bayless, K. J., Salazar, R., Davis, G. E.
(2000). RGD-Dependent Vacuolation and Lumen Formation Observed during Endothelial Cell Morphogenesis in Three-Dimensional Fibrin Matrices Involves the {alpha}v{beta}3 and {alpha}5{beta}1 Integrins. Am. J. Pathol.
156: 1673-1683
[Abstract][Full Text]
Roberts, T. M., Stewart, M.
(2000). Acting Like Actin: The Dynamics of the Nematode Major Sperm Protein (MSP) Cytoskeleton Indicate a Push-Pull Mechanism for Amoeboid Cell Motility. J. Cell Biol.
149: 7-12
[Abstract][Full Text]
Qualmann, B., Kelly, R. B.
(2000). Syndapin Isoforms Participate in Receptor-mediated Endocytosis and Actin Organization. J. Cell Biol.
148: 1047-1062
[Abstract][Full Text]
Chellaiah, M., Kizer, N., Silva, M., Alvarez, U., Kwiatkowski, D., Hruska, K. A.
(2000). Gelsolin Deficiency Blocks Podosome Assembly and Produces Increased Bone Mass and Strength. J. Cell Biol.
148: 665-678
[Abstract][Full Text]
Machesky, L. M.
(2000). The Tails of Two Myosins. J. Cell Biol.
148: 219-222
[Abstract][Full Text]
Evangelista, M., Klebl, B. M., Tong, A. H.Y., Webb, B. A., Leeuw, T., Leberer, E., Whiteway, M., Thomas, D. Y., Boone, C.
(2000). A Role for Myosin-I in Actin Assembly through Interactions with Vrp1p, Bee1p, and the Arp2/3 Complex. J. Cell Biol.
148: 353-362
[Abstract][Full Text]
DeRosier, D. J., Tilney, L. G.
(2000). F-Actin Bundles Are Derivatives of Microvilli: What Does This Tell Us about How Bundles Might Form?. J. Cell Biol.
148: 1-6
[Abstract][Full Text]
Noegel, A., Schleicher, M
(2000). The actin cytoskeleton of Dictyostelium: a story told by mutants. J. Cell Sci.
113: 759-766
[Abstract]
Ku, N.-O., Zhou, X., Toivola, D. M., Omary, M. B.
(1999). The cytoskeleton of digestive epithelia in health and disease. Am. J. Physiol. Gastrointest. Liver Physiol.
277: G1108-G1137
[Abstract][Full Text]
Carlier, M.-F., Nioche, P., Broutin-L'Hermite, I., Boujemaa, R., Le Clainche, C., Egile, C., Garbay, C., Ducruix, A., Sansonetti, P., Pantaloni, D.
(2000). GRB2 Links Signaling to Actin Assembly by Enhancing Interaction of Neural Wiskott-Aldrich Syndrome Protein (N-WASp) with Actin-related Protein (ARP2/3) Complex. J. Biol. Chem.
275: 21946-21952
[Abstract][Full Text]
Calderwood, D. A., Shattil, S. J., Ginsberg, M. H.
(2000). Integrins and Actin Filaments: Reciprocal Regulation of Cell Adhesion and Signaling. J. Biol. Chem.
275: 22607-22610
[Full Text]
Yamaguchi, H., Miki, H., Suetsugu, S., Ma, L., Kirschner, M. W., Takenawa, T.
(2000). Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP. Proc. Natl. Acad. Sci. USA
97: 12631-12636
[Abstract][Full Text]
Lawrence, D. W., Comerford, K. M., Colgan, S. P.
(2002). Role of VASP in reestablishment of epithelial tight junction assembly after Ca2+ switch. Am. J. Physiol. Cell Physiol.
282: C1235-C1245
[Abstract][Full Text]