The concept of self-organization in cellular architecture

doi:10.1083/jcb.200108110

Published 15 October 2001. doi:10.1083/jcb.200108110

This Article

	Full Text
	PDF (Full Text)
	PPT slides of all figures
	Alert me when this article is cited
	Citation Map

Services

	Email this article
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new content in the JCB
	Download to citation manager

Citing Articles

	Citing Articles via HighWire
	Citing Articles via CrossRef
	Citing Articles via Google Scholar

Google Scholar

	Articles by Misteli, T.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Misteli, T.


Social Bookmarking

	What's this?

© The Rockefeller University Press, 0021-9525/2001/10/181 $5.00
The Journal of Cell Biology, Volume 155, Number 2, October 15, 2001 181-186

Mini-Reviews

The concept of self-organization in cellular architecture

Tom Misteli

National Cancer Institute, National Institutes of Health, Bethesda, MD 20892

Address correspondence to Tom Misteli, National Cancer Institute, National Institutes of Health, 41 Liberty Drive, Building 41/B, Bethesda, MD 20892. Tel.: (301) 402-3959 Fax: (520) 832-0970. E-mail: mistelit{at}mail.nih.gov

Abstract
In vivo microscopy has recently revealed the dynamic natureof many cellular organelles. The dynamic properties of severalcellular structures are consistent with a role for self-organizationin their formation, maintenance, and function; therefore, self-organizationmight be a general principle in cellular organization.

Key Words: self-organization; cytoskeleton; nucleus; Golgi complex; dynamics

Add to CiteULike CiteULike Add to Complore Complore Add to Connotea Connotea Add to Del.icio.us Del.icio.us Add to Digg Digg Add to Reddit Reddit Add to Technorati Technorati What's this?

This article has been cited by other articles:

Drin, G., Morello, V., Casella, J.-F., Gounon, P., Antonny, B. (2008). Asymmetric Tethering of Flat and Curved Lipid Membranes by a Golgin. Science 320: 670-673 [Abstract] [Full Text]
Hemmerich, P., Weidtkamp-Peters, S., Hoischen, C., Schmiedeberg, L., Erliandri, I., Diekmann, S. (2008). Dynamics of inner kinetochore assembly and maintenance in living cells. J. Cell Biol. 180: 1101-1114 [Abstract] [Full Text]
Padilla, P. I., Uhart, M., Pacheco-Rodriguez, G., Peculis, B. A., Moss, J., Vaughan, M. (2008). Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin. Proc. Natl. Acad. Sci. USA 105: 3357-3361 [Abstract] [Full Text]
Herrmann, A., Fleischer, K., Czajkowska, H., Muller-Newen, G., Becker, W. (2007). Characterization of cyclin L1 as an immobile component of the splicing factor compartment. FASEB J. 21: 3142-3152 [Abstract] [Full Text]
Park, H.-O., Bi, E. (2007). Central Roles of Small GTPases in the Development of Cell Polarity in Yeast and Beyond. Microbiol. Mol. Biol. Rev. 71: 48-96 [Abstract] [Full Text]
Marenduzzo, D., Finan, K., Cook, P. R. (2006). The depletion attraction: an underappreciated force driving cellular organization. J. Cell Biol. 175: 681-686 [Abstract] [Full Text]
Leung, A. K. L., Calabrese, J. M., Sharp, P. A. (2006). Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc. Natl. Acad. Sci. USA 103: 18125-18130 [Abstract] [Full Text]
Negi, S. S., Olson, M. O. J. (2006). Effects of interphase and mitotic phosphorylation on the mobility and location of nucleolar protein B23. J. Cell Sci. 119: 3676-3685 [Abstract] [Full Text]
Charrier, C., Ehrensperger, M.-V., Dahan, M., Levi, S., Triller, A. (2006). Cytoskeleton Regulation of Glycine Receptor Number at Synapses and Diffusion in the Plasma Membrane.. J. Neurosci. 26: 8502-8511 [Abstract] [Full Text]
Lemm, I., Girard, C., Kuhn, A. N., Watkins, N. J., Schneider, M., Bordonne, R., Luhrmann, R. (2006). Ongoing U snRNP Biogenesis Is Required for the Integrity of Cajal Bodies. Mol. Biol. Cell 17: 3221-3231 [Abstract] [Full Text]
Fraser, P., Engel, J. D. (2006). Constricting restricted transcription: the (actively?) shrinking web. Genes Dev. 20: 1379-1383 [Full Text]
Renvoise, B., Khoobarry, K., Gendron, M.-C., Cibert, C., Viollet, L., Lefebvre, S. (2006). Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells. J. Cell Sci. 119: 680-692 [Abstract] [Full Text]
Reilein, A., Yamada, S., Nelson, W. J. (2005). Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells. J. Cell Biol. 171: 845-855 [Abstract] [Full Text]
Harold, F. M. (2005). Molecules into Cells: Specifying Spatial Architecture. Microbiol. Mol. Biol. Rev. 69: 544-564 [Abstract] [Full Text]
Voss, T. C., Demarco, I. A., Booker, C. F., Day, R. N. (2005). Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus. J. Cell Sci. 118: 3277-3288 [Abstract] [Full Text]
Doubrovinski, K., Howard, M. (2005). Stochastic model for Soj relocation dynamics in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 102: 9808-9813 [Abstract] [Full Text]
Riedel, I. H., Kruse, K., Howard, J. (2005). A Self-Organized Vortex Array of Hydrodynamically Entrained Sperm Cells. Science 309: 300-303 [Abstract] [Full Text]
Solovjeva, L., Svetlova, M., Sasina, L., Tanaka, K., Saijo, M., Nazarov, I., Bradbury, M., Tomilin, N. (2005). High Mobility of Flap Endonuclease 1 and DNA Polymerase {eta} Associated with Replication Foci in Mammalian S-Phase Nucleus. Mol. Biol. Cell 16: 2518-2528 [Abstract] [Full Text]
West, A. G., Fraser, P. (2005). Remote control of gene transcription. Hum Mol Genet 14: R101-R111 [Abstract] [Full Text]
Stein, G. S. (2005). Mechanogenomic Control of DNA Exposure and Sequestration. Am. J. Pathol. 166: 959-962 [Full Text]
Howard, M., Kruse, K. (2005). Cellular organization by self-organization: mechanisms and models for Min protein dynamics. J. Cell Biol. 168: 533-536 [Abstract] [Full Text]
Misteli, T. (2005). Going in GTP cycles in the nucleolus. J. Cell Biol. 168: 177-178 [Abstract] [Full Text]
Colau, G., Thiry, M., Leduc, V., Bordonne, R., Lafontaine, D. L. J. (2004). The Small Nucle(ol)ar RNA Cap Trimethyltransferase Is Required for Ribosome Synthesis and Intact Nucleolar Morphology. Mol. Cell. Biol. 24: 7976-7986 [Abstract] [Full Text]
Wedlich-Soldner, R., Wai, S. C., Schmidt, T., Li, R. (2004). Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling. J. Cell Biol. 166: 889-900 [Abstract] [Full Text]
Kosak, S. T., Groudine, M. (2004). Form follows function: the genomic organization of cellular differentiation. Genes Dev. 18: 1371-1384 [Abstract] [Full Text]
Postma, M., Roelofs, J., Goedhart, J., Loovers, H. M., Visser, A. J. W. G., Van Haastert, P. J. M. (2004). Sensitization of Dictyostelium chemotaxis by phosphoinositide-3-kinase-mediated self-organizing signalling patches. J. Cell Sci. 117: 2925-2935 [Abstract] [Full Text]
Kamada, A., Nagaya, H., Tamura, T., Kinjo, M., Jin, H.-Y., Yamashita, T., Jimbow, K., Kanoh, H., Wada, I. (2004). Regulation of Immature Protein Dynamics in the Endoplasmic Reticulum. J. Biol. Chem. 279: 21533-21542 [Abstract] [Full Text]
Tseng, Y., Lee, J. S. H., Kole, T. P., Jiang, I., Wirtz, D. (2004). Micro-organization and visco-elasticity of the interphase nucleus revealed by particle nanotracking. J. Cell Sci. 117: 2159-2167 [Abstract] [Full Text]
Hestiantoro, A., Swaab, D. F. (2004). Changes in Estrogen Receptor-{alpha} and -{beta} in the Infundibular Nucleus of the Human Hypothalamus Are Related to the Occurrence of Alzheimer's Disease Neuropathology. J. Clin. Endocrinol. Metab. 89: 1912-1925 [Abstract] [Full Text]
Padilla, P. I., Pacheco-Rodriguez, G., Moss, J., Vaughan, M. (2004). Nuclear localization and molecular partners of BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors. Proc. Natl. Acad. Sci. USA 101: 2752-2757 [Abstract] [Full Text]
Gordy, C., Mishra, S., Rodgers, W. (2004). Visualization of Antigen Presentation by Actin-Mediated Targeting of Glycolipid-Enriched Membrane Domains to the Immune Synapse of B Cell APCs. J. Immunol. 172: 2030-2038 [Abstract] [Full Text]
Herrmann, A., Sommer, U., Pranada, A. L., Giese, B., Kuster, A., Haan, S., Becker, W., Heinrich, P. C., Muller-Newen, G. (2004). STAT3 is enriched in nuclear bodies. J. Cell Sci. 117: 339-349 [Abstract] [Full Text]
Cook, P. R. (2003). Nongenic transcription, gene regulation and action at a distance. J. Cell Sci. 116: 4483-4491 [Abstract] [Full Text]
O'Brien, T. P., Bult, C. J., Cremer, C., Grunze, M., Knowles, B. B., Langowski, J., McNally, J., Pederson, T., Politz, J. C., Pombo, A., Schmahl, G., Spatz, J. P., van Driel, R. (2003). Genome Function and Nuclear Architecture: From Gene Expression to Nanoscience. Genome Res 13: 1029-1041 [Abstract] [Full Text]
Bosher, J. M., Hahn, B.-S., Legouis, R., Sookhareea, S., Weimer, R. M., Gansmuller, A., Chisholm, A. D., Rose, A. M., Bessereau, J.-L., Labouesse, M. (2003). The Caenorhabditis elegans vab-10 spectraplakin isoforms protect the epidermis against internal and external forces. J. Cell Biol. 161: 757-768 [Abstract] [Full Text]
Day, R. N., Voss, T. C., Enwright, J. F. III, Booker, C. F., Periasamy, A., Schaufele, F. (2003). Imaging the Localized Protein Interactions Between Pit-1 and the CCAAT/Enhancer Binding Protein {alpha} in the Living Pituitary Cell Nucleus. Mol. Endocrinol. 17: 333-345 [Abstract] [Full Text]
Wedlich-Soldner, R., Altschuler, S., Wu, L., Li, R. (2003). Spontaneous Cell Polarization Through Actomyosin-Based Delivery of the Cdc42 GTPase. Science 299: 1231-1235 [Abstract] [Full Text]
Kumaran, R. I., Muralikrishna, B., Parnaik, V. K. (2002). Lamin A/C speckles mediate spatial organization of splicing factor compartments and RNA polymerase II transcription. J. Cell Biol. 159: 783-793 [Abstract] [Full Text]
Scherl, A., Coute, Y., Deon, C., Calle, A., Kindbeiter, K., Sanchez, J.-C., Greco, A., Hochstrasser, D., Diaz, J.-J. (2002). Functional Proteomic Analysis of Human Nucleolus. Mol. Biol. Cell 13: 4100-4109 [Abstract] [Full Text]
Cornforth, M. N., Greulich-Bode, K. M., Loucas, B. D., Arsuaga, J., Vazquez, M., Sachs, R. K., Bruckner, M., Molls, M., Hahnfeldt, P., Hlatky, L., Brenner, D. J. (2002). Chromosomes are predominantly located randomly with respect to each other in interphase human cells. J. Cell Biol. 159: 237-244 [Abstract] [Full Text]
Lim, J.-H., Bustin, M., Ogryzko, V. V., Postnikov, Y. V. (2002). Metastable Macromolecular Complexes Containing High Mobility Group Nucleosome-binding Chromosomal Proteins in HeLa Nuclei. J. Biol. Chem. 277: 20774-20782 [Abstract] [Full Text]
Handwerger, K. E., Wu, Z.'a., Murphy, C., Gall, J. G. (2002). Heat shock induces mini-Cajal bodies in the Xenopus germinal vesicle. J. Cell Sci. 115: 2011-2020 [Abstract] [Full Text]