Published 24 December 2001. doi:10.1083/jcb.200108061
© The Rockefeller University Press,
0021-9525/2001/12/1103 $5.00
The Journal of Cell Biology, Volume 155, Number 7, December 24, 2001 1103-1108
Specific tetraspanin functions
Martin E. Hemler
Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115
Address correspondence to Martin E. Hemler, Dana-Farber Cancer Institute, Rm D-1430, 44 Binney St., Boston, MA 02115. Tel.: (617) 632-3410. Fax: (617) 632-2662. E-mail: martin_hemler{at}dfci.harvard.edu
Abstract
Relatively little attention has been given to the large family of abundantly expressed transmembrane proteins known as tetraspanins. Now, the importance of tetraspanins is strongly supported by emerging genetic evidence, coupled with new insights into the biochemistry and functions of tetraspanin protein complexes.

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