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Tarun M. Kapoor¹ and Duane A. Compton²

¹ Laboratory of Chemistry and Cell Biology, The Rockefeller University, New York, NY 10021
² Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755

Address correspondence to Tarun M. Kapoor, Laboratory of Chemistry and Cell Biology, The Rockefeller University, 1230 York Ave., New York, NY 10021. Tel.: (212) 327-8176. Fax: (212) 327-8177. E-mail: Kapoor{at}rockefeller.edu

Abstract
The contributions of key molecules predicted to align chromosomes at the center of the mitotic spindle have been recently examined. New results dictate that models for how chromosomes align during the early stages of mitosis must be revised to integrate properties of microtubule-based motor proteins as well as microtubule dynamics.

Key Words: chromosome; congression; traction fiber; poleward flux; kinesin

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