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Reviews Editor, The Journal of Cell Biology

Address correspondence to K.R. Dell, The Journal of Cell Biology, 1114 1st Ave., New York, NY 10021. Tel.: (415) 789-0982. Fax: (415) 476-5233. E-mail: kdell{at}itsa.ucsf.edu

How is the bidirectional motion of organelles controlled? In this issue, Deacon et al. (2003) reveal the unexpected finding that dynactin (previously known to control dynein-based motility) binds to kinesin II and regulates anterograde movement of Xenopus melanosomes. This result suggests that dynactin may be a key player in coordinating vesicle traffic in this system.

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