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Published 22 December 2003. doi:10.1083/jcb.200311123
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© The Rockefeller University Press, 0021-9525/2003/12/1189 $8.00
The Journal of Cell Biology, Volume 163, Number 6, 1189-1191

Comment

 Cup-ling oskar RNA localization and translational control

Paul Lasko

Department of Biology, McGill University, Montréal, Québec, Canada

Address correspondence to Paul Lasko, Department of Biology, McGill University, 115 West University Parkway, Montréal, Québec, Canada. Tel.: (514) 398-6401. Fax: (514) 398-5069. emial: Paul.Lasko{at}mcgill.ca

RNA localization and spatially restricted translational control can serve to deploy specific proteins to particular places within a cell. oskar (osk) RNA is a key initiatior of posterior patterning and germ cell specification in Drosophila, and its localization and translation are under elaborate control. In this issue, Wilhelm et al. (2003) show that the protein Cup both promotes osk localization and participates in repressing translation of unlocalized osk.

Abbreviations used in this paper: 4E-T, eIF4E transporter; Bru, Bruno; Btz, Barenstz; Exu, Exuperantia; Osk, Oskar; Yps, Ypsilon Schachtel.


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