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Published online April 21, 2008
doi:10.1083/jcb.200803126
The Journal of Cell Biology, Vol. 181, No. 2, 185-187
The Rockefeller University Press, 0021-9525 $30.00
© 2008 Rout
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 The peroxisome: a production in four acts

Michael P. Rout

Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY 10065

Correspondence to Michael P. Rout: rout{at}rockefeller.edu

A cell regulates the number, size, and kind of each organelle it possesses in response to its particular role in an environment or tissue. Yet we still know little about how the molecular signaling networks within each cell perform such regulation. In this issue, Saleem et al. (Saleem, R.A., B. Knoblach, F.D. Mast, J.J. Smith, J. Boyle, C.M. Dobson, R. Long-O'Donnell, R.A. Rachubinski, and J.D. Aitchison. 2008. J. Cell Biol. 181:281–292) show for the first time how groups of kinases and phosphatases are organized to control when and how a cell assembles one kind of organelle, the peroxisome.


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