ARTICLE

OLFACTORY CILIA IN THE FROG

T. S. Reese M.D.¹

¹ From the Laboratory of Neuroanatomical Sciences, National Institute of Neurological Diseases and Blindness, National Institutes of Health, United States Department of Health, Education, and Welfare, Public Health Service, Bethesda

Olfactory epithelium from the frog was examined in the living state by light microscopy and in the fixed state by electron microscopy. Particular attention was paid to the layer of cilia and mucus which covers the surface of the epithelium. The olfactory cilia differed from typical cilia in that they (a) arose from bipolar neurons and had centrioles near their basal bodies, (b) were up to 200 microns in length, of which the greater part was a distal segment containing an atypical array of ciliary fibers, (c) were often immotile, (d) had their distal segments arranged in parallel rows near the surface of the mucus, and (e) had many vesicles along their shafts and had splits in the array of fibers in their distal segments. These specializations make the olfactory cilia similar to cilia found on other sensory cells and support the theory that they are the locus where electrical excitation in the olfactory organ is initiated by contact with odorous substances.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

• Kleene, S. J. (2008). The Electrochemical Basis of Odor Transduction in Vertebrate Olfactory Cilia. Chem Senses 33: 839-859 [Abstract] [Full Text]  
• Scholey, J. M. (2008). Intraflagellar transport motors in cilia: moving along the cell's antenna. JCB 180: 23-29 [Abstract] [Full Text]  
• Pape, P. C., Fenelon, K., Lamboley, C. R. H., Stachura, D. (2007). Role of calsequestrin evaluated from changes in free and total calcium concentrations in the sarcoplasmic reticulum of frog cut skeletal muscle fibres. J. Physiol. 581: 319-367 [Abstract] [Full Text]  
• Ou, G., Koga, M., Blacque, O. E., Murayama, T., Ohshima, Y., Schafer, J. C., Li, C., Yoder, B. K., Leroux, M. R., Scholey, J. M. (2007). Sensory Ciliogenesis in Caenorhabditis elegans: Assignment of IFT Components into Distinct Modules Based on Transport and Phenotypic Profiles. Mol. Biol. Cell 18: 1554-1569 [Abstract] [Full Text]  
• Blacque, O. E., Li, C., Inglis, P. N., Esmail, M. A., Ou, G., Mah, A. K., Baillie, D. L., Scholey, J. M., Leroux, M. R. (2006). The WD Repeat-containing Protein IFTA-1 Is Required for Retrograde Intraflagellar Transport. Mol. Biol. Cell 17: 5053-5062 [Abstract] [Full Text]  
• Pan, X., Ou, G., Civelekoglu-Scholey, G., Blacque, O. E., Endres, N. F., Tao, L., Mogilner, A., Leroux, M. R., Vale, R. D., Scholey, J. M. (2006). Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors. JCB 174: 1035-1045 [Abstract] [Full Text]  
• Flannery, R. J., French, D. A., Kleene, S. J. (2006). Clustering of Cyclic-Nucleotide-Gated Channels in Olfactory Cilia. Biophys. J 91: 179-188 [Abstract] [Full Text]  
• Gomez, J., Neco, P., DiFranco, M., Vergara, J. L. (2006). Calcium Release Domains in Mammalian Skeletal Muscle Studied with Two-photon Imaging and Spot Detection Techniques. JGP 127: 623-637 [Abstract] [Full Text]  
• Evans, J. E., Snow, J. J., Gunnarson, A. L., Ou, G., Stahlberg, H., McDonald, K. L., Scholey, J. M. (2006). Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans. JCB 172: 663-669 [Abstract] [Full Text]  
• Fraser, J. A, Rang, C. E. J, Usher-Smith, J. A, Huang, C. L.-H (2005). Slow volume transients in amphibian skeletal muscle fibres studied in hypotonic solutions. J. Physiol. 564: 51-63 [Abstract] [Full Text]  
• Ursu, D., Schuhmeier, R. P., Melzer, W. (2005). Voltage-controlled Ca2+ release and entry flux in isolated adult muscle fibres of the mouse. J. Physiol. 562: 347-365 [Abstract] [Full Text]  
• Suzuki, S., Hino, N., Sugi, H. (2004). Intracellular calcium translocation during the contraction-relaxation cycle in scorpionfish swimbladder muscle. J. Exp. Biol. 207: 1093-1099 [Abstract] [Full Text]  
• Buckingham, S. D., Ali, D. W. (2004). Sodium and potassium currents of larval zebrafish muscle fibres. J. Exp. Biol. 207: 841-852 [Abstract] [Full Text]  
• CLAUSEN, T. (2003). Na+-K+ Pump Regulation and Skeletal Muscle Contractility. Physiol. Rev. 83: 1269-1324 [Abstract] [Full Text]  
• Novo, D., DiFranco, M., Vergara, J. L. (2003). Comparison between the Predictions of Diffusion-Reaction Models and Localized Ca2+ Transients in Amphibian Skeletal Muscle Fibers. Biophys. J 85: 1080-1097 [Abstract] [Full Text]  
• Paik, S. I., Lehman, M. N., Seiden, A. M., Duncan, H. J., Smith, D. V. (1992). Human Olfactory Biopsy: The Influence of Age and Receptor Distribution. Arch Otolaryngol Head Neck Surg 118: 731-738 [Abstract]  
• Afzelius, B. (1976). A human syndrome caused by immotile cilia. Science 193: 317-319 [Abstract]  
• Peachey, L. D. (1973). Electrical Events in the T-System of Frog Skeletal Muscle. Cold Spring Harb Symp Quant Biol 37: 479-487 [Abstract]  
• Tucker, D., Shibuya, T. (1965). A Physiologic and Pharmacologic Study of Olfactory Receptors. Cold Spring Harb Symp Quant Biol 30: 207-215 [Abstract]  
• Lettvin, J. Y., Gesteland, R. C. (1965). Speculations on Smell. Cold Spring Harb Symp Quant Biol 30: 217-225 [Abstract]  

Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents