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The Journal of Cell Biology, Vol 29, 287-292, Copyright © 1966 by Rockefeller University Press

ARTICLE

SECRETION OF alpha-AMYLASE BY THE EMBRYONIC CHICK PANCREAS IN VITRO

R. G. Kulka 1 and U. Yalovsky 1

1 From the Department of Biological Chemistry, The Hebrew University of Jerusalem, Israel

Pancreases taken from chick embryos secrete amylase in vitro when stimulated by cholinergic drugs. Rates of secretion increase with developmental age. The pancreas isolated together with the duodenal loop from the 8 day embryo is already capable of secretion in vitro. It is therefore concluded that the pancreas acquires the ability to secrete digestive enzymes more than 10 days before the beginning of the prominent biochemical and morphological changes associated with the maturation of the gland.

Submitted on December 28, 1965


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