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J. Biophys. and Biochem. Cytol., Vol 3, 89-94, Copyright © 1957 by Rockefeller University Press

ARTICLE

EFFECTS OF IONIC STRENGTH OF IMMERSION MEDIUM ON THE STRUCTURE OF PERIPHERAL NERVE MYELIN

J. B. Finean Ph.D.1 and P. F. Millington 1

1 From the Department of Medical Biochemistry and Pharmacology, University of Birmingham, England

A study of the effects of hypertonic solutions on the structure of peripheral nerve myelin reveals an expansion rather than a contraction of the layer spacing. This suggests the absence of "free" water between the myelin layers.

Hypotonic solutions bring about a change in radial repeat period from 171 A to 250 to 270 A.

These findings are of significance in relation to the structure of myelin.

 Submitted on November 16, 1956


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