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Epitomics: The Rabbit Monoclonal Company
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J. Biophys. and Biochem. Cytol., Vol 3, 503-504, Copyright © 1957 by Rockefeller University Press

BRIEF NOTES

Iron Particles in Normal Erythroblasts and Normal and Pathological Erythrocytes

Marcel C. Bessis 1 and Janine Breton-Gorius 1

1 From Centre National de Transfusion Sanguine, Paris, France.

Iron-containing granules (40 to 100 A in diameter), in groups or isolated, are present in normal erythroblasts, normoblasts, reticulocytes, and certain pathological erythrocytes. Similar granules are present in macrophages and have been noted in the stroma of erythrocytes following phagocytosis and hemolysis by macrophages. Incorporation of the granules from the macrophage into erythroblasts is presented as a process similar to pinocytosis. The presence of the iron-containing granules within the erythroid cells parallels hemoglobin synthesis.

Submitted on December 10, 1956


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