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J. Biophys. and Biochem. Cytol., Vol 5, 55-58, Copyright © 1959 by Rockefeller University Press

ARTICLE

The Absence of Histone in the Bacterium Escherichia coli : II. X-ray Diffraction of Nucleoprotein Extract



M. H. F. Wilkins Ph.D.1 and G. Zubay Ph.D.1

1 From the Medical Research Council, Biophysics Research Unit, King's College, London

X-ray diffraction photographs of a nucleoprotein preparation from Escherichia coli show the A-type pattern of crystalline deoxyribonucleic acid (DNA). This suggests that a large part of the DNA is free from protein. In higher organisms DNA does not exist in this form but is closely bound to protein.

Submitted on August 11, 1958


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