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The Journal of Cell Biology, Vol 80, 53-60, Copyright © 1979 by The Rockefeller University Press

ARTICLES

The angular distribution of directional changes of guided 3T3 cells

G Albrecht-Buehler

This paper reports that the angular distribution of directional change of 3T3 cells which followed guiding lines on a substrate and left the guidance at various angles shows a peculiar preference for angles between 30 degrees and 60 degrees. Regarding the phenomenon of cellular guidance itself, 3T3 cells faced with a choice between guiding lines toward different directions seem to explore various options before following one. This observation suggests that the outcome of a probing action and not substrate properties alone can explain the guidance behavior of 3T3 cells.
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