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The Journal of Cell Biology, Vol 96, 1815-1819, Copyright © 1983 by The Rockefeller University Press

ARTICLES

Generation of an internal matrix in mature avian erythrocyte nuclei during reactivation in cytoplasts

RE LaFond, H Woodcock, CL Woodcock, ER Kundahl and JJ Lucas

When fused with mouse L-cell cytoplasts, chick erythrocyte nuclei enlarge, take up proteins from the host cytoplasm, and recommence RNA synthesis. We found that during this transition the erythrocyte nuclei gain an internal nuclear matrix, thus providing a novel approach to questions concerning the nature of the salt-resistant intranuclear skeleton. A new method for preparation and examination of the nuclear matrix in situ is also described.
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