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Custom Peptide Synthesis
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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200304031
Goldfinger et al.

• Video 1 (1.7 MB) Cell-bearing wt {alpha}4 exhibit lamellipodial persistence and directed migration.

• Video 2 (3.5 MB) The phosphorylation-resistant {alpha}4(S988A) mutation de-stabilizes lamellipodia and inhibits migration.

• Video 3 (6.6 MB) Enforced association of paxillin with {alpha}4 integrin inhibits migration.

• Figure 1 {alpha}4(S988A) and {alpha}4 COOH-terminal paxillin fusion do not perturb {alpha}4 integrin-dependent adhesion in CHO cells.

• Figure 2 Paxillin colocalizes with nonphosphorylated {alpha}4 at the lateral and trailing edges but not with phospho-{alpha}4 at the leading edge in wounded confluent monolayers.





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