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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200407113
Damm et al.

Figure S1 Cav-1KO and HuH7 cells do not contain cav-1.

Figure S2 Internalization and infection of SV40 occurs independently of Eps15 and Dynamin II.

Figure S3 Latrunculin A treatment does not inhibit infection with SV40 in HuH7 cells but in cav-1KO cells.

Figure S4 SV40 containing endosomes are pH neutral, disconnected from the plasma membrane, and different to vesicles of the classical endosomal pathway.

Figure S5 18 h after internalization, SV40 ends up in the smooth ER.

Video 1 (3.5 MB) AF594-SV40 enters cytosolic organelles in cav-1KO cells.

Video 2 (504 K) AF594-SV40 enters cytosolic organelles in cav-1KO cells (detail).

Video 3 (2.8 MB) SV40-containing vesicular and tubular carriers interact with microtubules.

Video 4 (504 K) Virus-induced activation of cytosolic organelles.

Video 5 (5.5 MB) SV40 internalization in cav-1KO cells treated with nocodazole.

Video 6 (8.4 MB) SV40 entry into cav-1KO cells transfected with cav-1.

Video 7 (5.8 MB) Internalized SV40 enters caveosomes in cav-1KO cells expressing caveolin-1.

Video 8 (4.9 MB) Caveolin-negative SV40 particles merge with preexisting caveosomes in cav-1WT cells.





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