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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200708022
Zoeller et al.
• Figure S1 Analysis of Danio rerio domain V/endorepellin.
• Figure S2 Comparison of MO-DI and MO-DV perlecan morphants and p53 coknockdown experiments.
• Figure S3 Perlecan morphants display an abnormal muscular structure at 2 dpf.
• Figure S4 The effects of MO-DI–mediated perlecan knockdown on vascular development are maintained at 3–4 dpf.
• Figure S5 Vascular analysis in Tg(fli1:egfp)y1 and Tg(vegfr2:g-rcfp) perlecan morphant embryos.
• Video 1 Perlecan morphants have a bent phenotype and swim in a circular fashion.
• Video 2 Regular circulation through the heart, head, and axial vessels in a control 3-dpf zebrafish.
• Video 3 Perlecan morphant at 3 dpf with a severe phenotype showing the complete absence of circulating blood cells in spite of robust heart contraction.
• Video 4 Regular circulation through the trunk vessels in a control 3-dpf zebrafish.
• Video 5 Abnormal trunk vessel circulation in a perlecan morphant at 3 dpf.
• Video 6 Severely reduced circulation through the trunk vessels in a perlecan morphant at 3 dpf.
• Tables (PDF)
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