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Index of Online Supplemental Material for
J. Cell Biol. 10.1083/jcb.200709030
Mazroui et al.
• Figure S1 Cells exposed to heat stress require HuR protein to trigger caspase-dependent apoptosis.
• Figure S2 50 nM AP–HuR-GST or AP-GST, a nontoxic dose, enters HeLa cells with high efficiency.
• Figure S3 Depletion of HuR expression by RNAi prevented casp-3 activation upon prolonged inhibition of the ubiquitin–proteasome pathway.
• Figure S4 The PAN caspase inhibitor zVAD does not prevent STS-mediated cytoplasmic translocation of HuR.
• Figure S5 Schematic representation of the different steps of the in vitro assay for apoptosome activity
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