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Cover picture: Primary mouse keratinocytes grown under conditions that limit cell-cell adhesion. Confocal microscopy of cells labeled with antibodies against Keratin 5 (green), DAPI (blue), and ACF7 (red). ACF7, an orthologue of the fly kakapo protein, is an unusual plakin that displays most prominent association with the peripheral ends of microtubules, and it also binds to actin filaments, but shows little or no association with the keratin cytoskeleton. See related article in this issue by Karakesisoglou et al., 195-208.
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