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Cover picture: Kinesin motor proteins transporting vesicular cargo along microtubules. The two catalytic core domains (purple) move in a hand-over-hand manner along a protofilament row of tubulin subunits. The neck region (yellow) plays a critical role in the mechanism of this processive motion, as described in Tomishighe and Vale (1081-1092) and Thorn et al. (1093-1100) in this issue. Cover art was produced by Graham Johnson.
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