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Dec 20 2004; 167 (6)
 News  In This Issue
  Research Roundup
 Research Articles  Reports
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 Of Interest  From J. Exp. Med.

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  N e w s

In This Issue:

In This Issue [PDF]
Measuring insulin [Full Text]  
PINCHing together integrins and signaling [Full Text]  
Clustering in integrin binding [Full Text]  
Targeting the inner nuclear membrane [Full Text]  
Stick hard, signal fast [Full Text]  

Research Roundup:

Research Roundup [PDF]
Dynamin in fission and fusion [Full Text]  
Opening closed pores [Full Text]  
Insulin breaks hearts [Full Text]  
Time keepers abound [Full Text]  
Checking in on spindle size [Full Text]  

  R e s e a r c h    A r t i c l e s

Reports:

Reconstitution of COPII vesicle fusion to generate a pre-Golgi intermediate compartment
Dalu Xu and Jesse C. Hay
J. Cell Biol. 2004 167: 997-1003. Published Dec 20 2004, 10.1083/jcb.200408135. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca2+ signaling
Ying Jie Wang, Wen Hong Li, Jing Wang, Ke Xu, Ping Dong, Xiang Luo, and Helen L. Yin
J. Cell Biol. 2004 167: 1005-1010. Published Dec 20 2004, 10.1083/jcb.200408008. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Processive capping by formin suggests a force-driven mechanism of actin polymerization
Michael M. Kozlov and Alexander D. Bershadsky
J. Cell Biol. 2004 167: 1011-1017. Published Dec 13 2004, 10.1083/jcb.200410017. [Abstract] [Full Text] [PDF]  

The integrin effector PINCH regulates JNK activity and epithelial migration in concert with Ras suppressor 1
Julie L. Kadrmas, Mark A. Smith, Kathleen A. Clark, Stephen M. Pronovost, Nemone Muster, John R. Yates, III, and Mary C. Beckerle
J. Cell Biol. 2004 167: 1019-1024. Published Dec 13 2004, 10.1083/jcb.200408090. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Articles:

Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome
Kathrin Plath, Dale Talbot, Karien M. Hamer, Arie P. Otte, Thomas P. Yang, Rudolf Jaenisch, and Barbara Panning
J. Cell Biol. 2004 167: 1025-1035. Published Dec 13 2004, 10.1083/jcb.200409026. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

The spindle assembly checkpoint is not essential for CSF arrest of mouse oocytes
Chizuko Tsurumi, Steffen Hoffmann, Stephan Geley, Ralph Graeser, and Zbigniew Polanski
J. Cell Biol. 2004 167: 1037-1050. Published Dec 20 2004, 10.1083/jcb.200405165. [Abstract] [Full Text] [PDF]  

Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore
Tomoyuki Ohba, Eric C. Schirmer, Takeharu Nishimoto, and Larry Gerace
J. Cell Biol. 2004 167: 1051-1062. Published Dec 20 2004, 10.1083/jcb.200409149. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in ß-cells
Mirko Trajkovski, Hassan Mziaut, Anke Altkrüger, Joke Ouwendijk, Klaus-Peter Knoch, Stefan Müller, and Michele Solimena
J. Cell Biol. 2004 167: 1063-1074. Published Dec 13 2004, 10.1083/jcb.200408172. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70–CHIP E3 ubiquitin ligase
J. Michael Younger, Hong-Yu Ren, Liling Chen, Chun-Yang Fan, Andrea Fields, Cam Patterson, and Douglas M. Cyr
J. Cell Biol. 2004 167: 1075-1085. Published Dec 20 2004, 10.1083/jcb.200410065. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Interdependent assembly of specific regulatory lipids and membrane fusion proteins into the vertex ring domain of docked vacuoles
Rutilio A. Fratti, Youngsoo Jun, Alexey J. Merz, Nathan Margolis, and William Wickner
J. Cell Biol. 2004 167: 1087-1098. Published Dec 20 2004, 10.1083/jcb.200409068. [Abstract] [Full Text] [PDF]  

Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane
Marcello Marelli, Jennifer J. Smith, Sunhee Jung, Eugene Yi, Alexey I. Nesvizhskii, Rowan H. Christmas, Ramsey A. Saleem, Yuen Yi C. Tam, Andrei Fagarasanu, David R. Goodlett, Ruedi Aebersold, Richard A. Rachubinski, and John D. Aitchison
J. Cell Biol. 2004 167: 1099-1112. Published Dec 13 2004, 10.1083/jcb.200404119. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

The interplay of osteogenesis and hematopoiesis: expression of a constitutively active PTH/PTHrP receptor in osteogenic cells perturbs the establishment of hematopoiesis in bone and of skeletal stem cells in the bone marrow
Sergei A. Kuznetsov, Mara Riminucci, Navid Ziran, Takeo W. Tsutsui, Alessandro Corsi, Laura Calvi, Henry M. Kronenberg, Ernestina Schipani, Pamela Gehron Robey, and Paolo Bianco
J. Cell Biol. 2004 167: 1113-1122. Published Dec 20 2004, 10.1083/jcb.200408079. [Abstract] [Full Text] [PDF]  

The diabetes-linked transcription factor PAX4 promotes ß-cell proliferation and survival in rat and human islets
Thierry Brun, Isobel Franklin, Luc St-Onge, Anna Biason-Lauber, Eugene J. Schoenle, Claes B. Wollheim, and Benoit R. Gauthier
J. Cell Biol. 2004 167: 1123-1135. Published Dec 13 2004, 10.1083/jcb.200405148. [Abstract] [Full Text] [PDF]  

Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble
Jennifer Zeitler, Cynthia P. Hsu, Heather Dionne, and David Bilder
J. Cell Biol. 2004 167: 1137-1146. Published Dec 20 2004, 10.1083/jcb.200407158. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophy
Ranjana Arya, Vishram Kedar, Jae Ryoung Hwang, Holly McDonough, Hui-Hua Li, Joan Taylor, and Cam Patterson
J. Cell Biol. 2004 167: 1147-1159. Published Dec 13 2004, 10.1083/jcb.200402033. [Abstract] [Full Text] [PDF]  

Persistence of apoptotic cells without autoimmune disease or inflammation in CD14–/– mice
Andrew Devitt, Kate G. Parker, Carol Anne Ogden, Ceri Oldreive, Michael F. Clay, Lynsey A. Melville, Christopher O. Bellamy, Adam Lacy-Hulbert, Sophie C. Gangloff, Sanna M. Goyert, and Christopher D. Gregory
J. Cell Biol. 2004 167: 1161-1170. Published Dec 20 2004, 10.1083/jcb.200410057. [Abstract] [Full Text] [PDF]  

TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase
Elena Goncharova, Dmitry Goncharov, Daniel Noonan, and Vera P. Krymskaya
J. Cell Biol. 2004 167: 1171-1182. Published Dec 20 2004, 10.1083/jcb.200405130. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Force measurements in E-cadherin–mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42
Yeh-Shiu Chu, William A. Thomas, Olivier Eder, Frederic Pincet, Eric Perez, Jean Paul Thiery, and Sylvie Dufour
J. Cell Biol. 2004 167: 1183-1194. Published Dec 13 2004, 10.1083/jcb.200403043. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases
Xiang-Tian Kong, Fang-Ming Deng, Ping Hu, Feng-Xia Liang, Ge Zhou, Anna B. Auerbach, Nancy Genieser, Peter K. Nelson, Edith S. Robbins, Ellen Shapiro, Bechara Kachar, and Tung-Tien Sun
J. Cell Biol. 2004 167: 1195-1204. Published Dec 20 2004, 10.1083/jcb.200406025. [Abstract] [Full Text] [PDF]  

BDNF-induced recruitment of TrkB receptor into neuronal lipid rafts: roles in synaptic modulation
Shingo Suzuki, Tadahiro Numakawa, Kazuhiro Shimazu, Hisatsugu Koshimizu, Tomoko Hara, Hiroshi Hatanaka, Lin Mei, Bai Lu, and Masami Kojima
J. Cell Biol. 2004 167: 1205-1215. Published Dec 13 2004, 10.1083/jcb.200404106. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

The adhesion force of Notch with Delta and the rate of Notch signaling
Francois Ahimou, Lee-Peng Mok, Boris Bardot, and Cedric Wesley
J. Cell Biol. 2004 167: 1217-1229. Published Dec 20 2004, 10.1083/jcb.200407100. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Palmitoylation supports assembly and function of integrin–tetraspanin complexes
Xiuwei Yang, Oleg V. Kovalenko, Wei Tang, Christoph Claas, Christopher S. Stipp, and Martin E. Hemler
J. Cell Biol. 2004 167: 1231-1240. Published Dec 20 2004, 10.1083/jcb.200404100. [Abstract] [Full Text] [PDF]  

The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}Lß2
Minsoo Kim, Christopher V. Carman, Wei Yang, Azucena Salas, and Timothy A. Springer
J. Cell Biol. 2004 167: 1241-1253. Published Dec 20 2004, 10.1083/jcb.200404160. [Abstract] [Full Text] [PDF] [Supplemental Material Index]  

Corrections:

Correction
Brendan D. Manning J. Cell Biol. 2004 167: 1255. Published Dec 20 2004, 10.1083/jcb200408161113004c. [Full Text] [PDF]  

  O f    I n t e r e s t

From J. Exp. Med.:

Dynamic repositioning of CD4 and CD8 genes during T cell development
Stephanie Delaire, Yina Hsing Huang, Shaio Wei Chan, and Ellen A. Robey
[Full Text]  

T cell cross-reactivity and conformational changes during TCR engagement
Jean K. Lee, Guillaume Stewart-Jones, Tao Dong, Karl Harlos, Kati Di Gleria, Lucy Dorrell, Daniel C. Douek, P. Anton van der Merwe, E. Yvonne Jones, and Andrew J. McMichael
[Full Text]  

Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice
Matthias Merkenschlager, Shannon Amoils, Esther Roldan, Amin Rahemtulla, Eric O'Connor, Amanda G. Fisher, and Karen E. Brown
[Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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