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The Journal of Cell Biology
Supplemental Material

Supplemental material related to the following articles is available online:

From the Current Issue: 182 (1); [Table of Contents]

Dominique Kranz, Christoph Dohmesen, and Matthias Dobbelstein
BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathways
JCB 2008; 182(1): 197-213 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material index]

Yunhao Liu, Daniel Timothy Sweet, Mohamad Irani-Tehrani, Nobuyo Maeda, and Ellie Tzima
Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation
JCB 2008; 182(1): 185-196 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

James E. Vince, Diep Chau, Bernard Callus, W. Wei-Lynn Wong, Christine J. Hawkins, Pascal Schneider, Mark McKinlay, Christopher A. Benetatos, Stephen M. Condon, Srinivas K. Chunduru, George Yeoh, Robert Brink, David L. Vaux, and John Silke
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNF{alpha}
JCB 2008; 182(1): 171-184 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Tsukasa Oikawa, Toshiki Itoh, and Tadaomi Takenawa
Sequential signals toward podosome formation in NIH-src cells
JCB 2008; 182(1): 157-169 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Hsu-Wen Chao, Chen-Jei Hong, Tzyy-Nan Huang, Yi-Ling Lin, and Yi-Ping Hsueh
SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis
JCB 2008; 182(1): 141-155 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jiefei Geng, Misuzu Baba, Usha Nair, and Daniel J. Klionsky
Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy
JCB 2008; 182(1): 129-140 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material index]

Stefan A. Paschen, Jan G. Christian, Juliane Vier, Franziska Schmidt, Axel Walch, David M. Ojcius, and Georg Häcker
Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease
JCB 2008; 182(1): 117-127 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material index]

Eva Szabo, Yuanyuan Qiu, Shairaz Baksh, Marek Michalak, and Michal Opas
Calreticulin inhibits commitment to adipocyte differentiation
JCB 2008; 182(1): 103-116 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Dinghai Zheng, Nader Ezzeddine, Chyi-Ying A. Chen, Wenmiao Zhu, Xiangwei He, and Ann-Bin Shyu
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
JCB 2008; 182(1): 89-101 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material index]

Sarah Woolner, Lori L. O'Brien, Christiane Wiese, and William M. Bement
Myosin-10 and actin filaments are essential for mitotic spindle function
JCB 2008; 182(1): 77-88 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jan M. Pawlicki and Joan A. Steitz
Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production
JCB 2008; 182(1): 61-76 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material index]

Ville O. Paavilainen, Esko Oksanen, Adrian Goldman, and Pekka Lappalainen
Structure of the actin-depolymerizing factor homology domain in complex with actin
JCB 2008; 182(1): 51-59 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material index]

Yu-Qian Zhang and Kevin D. Sarge
Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies
JCB 2008; 182(1): 35-39 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Shengjiang Tan, Ekaterina Lyulcheva, Jon Dean, and Daimark Bennett
Mars promotes dTACC dephosphorylation on mitotic spindles to ensure spindle stability
JCB 2008; 182(1): 27-33 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material index]

Paola Bonetti, Teresa Davoli, Cristina Sironi, Bruno Amati, Pier Giuseppe Pelicci, and Emanuela Colombo
Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7{gamma}
JCB 2008; 182(1): 19-26 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material index]

From Past Issues:

Motoring microvillar membrane
JCB 2007; published online before print, 10.1083/jcb.1774iti5v1 [Full Text]  
Article supplement(s): [CORRECTION]

Sudha Kumari, Virginia Borroni, Ashutosh Chaudhry, Baron Chanda, Ramiro Massol, Satyajit Mayor, and Francisco J. Barrantes
Nicotinic acetylcholine receptor is internalized via a Rac-dependent, dynamin-independent endocytic pathway
JCB 2008; 181(7): 1179-1193 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Yong Jik Lee, Amy Szumlanski, Erik Nielsen, and Zhenbiao Yang
Rho-GTPase–dependent filamentous actin dynamics coordinate vesicle targeting and exocytosis during tip growth
JCB 2008; 181(7): 1155-1168 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Feng-Qian Li, Adaobi Mofunanya, Kimberley Harris, and Ken-Ichi Takemaru
Chibby cooperates with 14-3-3 to regulate β-catenin subcellular distribution and signaling activity
JCB 2008; 181(7): 1141-1154 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Robert W. Gilkerson, Eric A. Schon, Evelyn Hernandez, and Mercy M. Davidson
Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation
JCB 2008; 181(7): 1117-1128 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Kim N. Green, Angelo Demuro, Yama Akbari, Brian D. Hitt, Ian F. Smith, Ian Parker, and Frank M. LaFerla
SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production
JCB 2008; 181(7): 1107-1116 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Daniel C. Scott and Randy Schekman
Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins
JCB 2008; 181(7): 1095-1105 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Soma Banerjee, Stephanie Smith, Ji-Hyun Oum, Hung-Jiun Liaw, Ji-Young Hwang, Nilabja Sikdar, Akira Motegi, Sang Eun Lee, and Kyungjae Myung
Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination
JCB 2008; 181(7): 1083-1093 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Nadia Vadaie, Heather Dionne, Darowan S. Akajagbor, Seth R. Nickerson, Damian J. Krysan, and Paul J. Cullen
Cleavage of the signaling mucin Msb2 by the aspartyl protease Yps1 is required for MAPK activation in yeast
JCB 2008; 181(7): 1073-1081 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Daisuke Hashimoto, Masaki Ohmuraya, Masahiko Hirota, Akitsugu Yamamoto, Koichi Suyama, Satoshi Ida, Yuushi Okumura, Etsuhisa Takahashi, Hiroshi Kido, Kimi Araki, Hideo Baba, Noboru Mizushima, and Ken-ichi Yamamura
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells
JCB 2008; 181(7): 1065-1072 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Rajini Mudhasani, Zhiqing Zhu, Gyorgy Hutvagner, Christine M. Eischen, Stephen Lyle, Lisa L. Hall, Jeanne B. Lawrence, Anthony N. Imbalzano, and Stephen N. Jones
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells
JCB 2008; 181(7): 1055-1063 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

John W. Goss and Derek K. Toomre
Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis
JCB 2008; 181(7): 1047-1054 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Junghoon Ha, Kevin W.-H. Lo, Kenneth R. Myers, Tiffany M. Carr, Michael K. Humsi, Bareza A. Rasoul, Rosalind A. Segal, and K. Kevin Pfister
A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes
JCB 2008; 181(6): 1027-1039 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Mark D. Bass, Mark R. Morgan, Kirsty A. Roach, Jeffrey Settleman, Andrew B. Goryachev, and Martin J. Humphries
p190RhoGAP is the convergence point of adhesion signals from {alpha}5β1 integrin and syndecan-4
JCB 2008; 181(6): 1013-1026 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Hsiao-Hui Lee and Zee-Fen Chang
Regulation of RhoA-dependent ROCKII activation by Shp2
JCB 2008; 181(6): 999-1012 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Mika Sakurai-Yageta, Chiara Recchi, Gaëlle Le Dez, Jean-Baptiste Sibarita, Laurent Daviet, Jacques Camonis, Crislyn D'Souza-Schorey, and Philippe Chavrier
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
JCB 2008; 181(6): 985-998 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Runxiang Qiu, Xiuyun Wang, Alice Davy, Chen Wu, Kiyohito Murai, Heying Zhang, John G. Flanagan, Philippe Soriano, and Qiang Lu
Regulation of neural progenitor cell state by ephrin-B
JCB 2008; 181(6): 973-983 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Xueni Li, Mei Huang, Huiling Zheng, Yinyin Wang, Fangli Ren, Yu Shang, Yonggong Zhai, David M. Irwin, Yuguang Shi, Di Chen, and Zhijie Chang
CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation
JCB 2008; 181(6): 959-972 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Yong Tian, Caroline Pate, Alberto Andreolotti, Limin Wang, Elaine Tuomanen, Kelli Boyd, Enrique Claro, and Suzanne Jackowski
Cytokine secretion requires phosphatidylcholine synthesis
JCB 2008; 181(6): 945-957 [Abstract] [Full Text]  
Article supplement(s): [ Supplemental Material Index]

Dieter Kressler, Daniela Roser, Brigitte Pertschy, and Ed Hurt
The AAA ATPase Rix7 powers progression of ribosome biogenesis by stripping Nsa1 from pre-60S particles
JCB 2008; 181(6): 935-944 [Abstract] [Full Text]  
Article supplement(s): [ Supplemental Material Index]

Jonathan D. Ellis, David Llères, Marco Denegri, Angus I. Lamond, and Javier F. Cáceres
Spatial mapping of splicing factor complexes involved in exon and intron definition
JCB 2008; 181(6): 921-934 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jonathan E. Grim, Michael P. Gustafson, Roli K. Hirata, Amanda C. Hagar, Jherek Swanger, Markus Welcker, Harry C. Hwang, Johan Ericsson, David W. Russell, and Bruce E. Clurman
Isoform- and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase
JCB 2008; 181(6): 913-920 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Lilli Winter, Christina Abrahamsberg, and Gerhard Wiche
Plectin isoform 1b mediates mitochondrion–intermediate filament network linkage and controls organelle shape
JCB 2008; 181(6): 903-911 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Anthony Tighe, Oliver Staples, and Stephen Taylor
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores
JCB 2008; 181(6): 893-901 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Isabel Jaco, Andrés Canela, Elsa Vera, and Maria A. Blasco
Centromere mitotic recombination in mammalian cells
JCB 2008; 181(6): 885-892 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Nattapon Panupinthu, Joseph T. Rogers, Lin Zhao, Luis Pastor Solano-Flores, Fred Possmayer, Stephen M. Sims, and S. Jeffrey Dixon
P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis
JCB 2008; 181(5): 859-871 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Nicholas C. Kappas, Gefei Zeng, John C. Chappell, Joseph B. Kearney, Surovi Hazarika, Kimberly G. Kallianos, Cam Patterson, Brian H. Annex, and Victoria L. Bautch
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching
JCB 2008; 181(5): 847-858 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Sergio Leal-Ortiz, Clarissa L. Waites, Ryan Terry-Lorenzo, Pedro Zamorano, Eckart D. Gundelfinger, and Craig C. Garner
Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis
JCB 2008; 181(5): 831-846 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Tadayuki Shimada, Michinori Toriyama, Kaori Uemura, Hiroyuki Kamiguchi, Tadao Sugiura, Naoki Watanabe, and Naoyuki Inagaki
Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth
JCB 2008; 181(5): 817-829 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Chuan-En Wang, Hui Zhou, John R. McGuire, Vincenzo Cerullo, Brendan Lee, Shi-Hua Li, and Xiao-Jiang Li
Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin
JCB 2008; 181(5): 803-816 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Xiao-Wei Chen, Ya-Qin Feng, Chan-Juan Hao, Xiao-Li Guo, Xin He, Zhi-Yong Zhou, Ning Guo, Hong-Ping Huang, Wei Xiong, Hui Zheng, Pan-Li Zuo, Claire Xi Zhang, Wei Li, and Zhuan Zhou
DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release
JCB 2008; 181(5): 791-801 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Roger Albertson, Jian Cao, Tao-shih Hsieh, and William Sullivan
Vesicles and actin are targeted to the cleavage furrow via furrow microtubules and the central spindle
JCB 2008; 181(5): 777-790 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Panagiota Panagopoulou, Constantinos H. Davos, Derek J. Milner, Emily Varela, JoAnn Cameron, Douglas L. Mann, and Yassemi Capetanaki
Desmin mediates TNF-{alpha}–induced aggregate formation and intercalated disk reorganization in heart failure
JCB 2008; 181(5): 761-775 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Subhanjan Mondal, Deenadayalan Bakthavatsalam, Paul Steimle, Berthold Gassen, Francisco Rivero, and Angelika A. Noegel
Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions
JCB 2008; 181(5): 747-760 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Damien Laporte, Bénédicte Salin, Bertrand Daignan-Fornier, and Isabelle Sagot
Reversible cytoplasmic localization of the proteasome in quiescent yeast cells
JCB 2008; 181(5): 737-745 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Katherine Minter-Dykhouse, Irene Ward, Michael S.Y. Huen, Junjie Chen, and Zhenkun Lou
Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis
JCB 2008; 181(5): 727-735 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Patryk Konieczny, Peter Fuchs, Siegfried Reipert, Wolfram S. Kunz, Anikó Zeöld, Irmgard Fischer, Denise Paulin, Rolf Schröder, and Gerhard Wiche
Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms
JCB 2008; 181(4): 667-681 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Gábor Juhász, Jahda H. Hill, Ying Yan, Miklós Sass, Eric H. Baehrecke, Jonathan M. Backer, and Thomas P. Neufeld
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila
JCB 2008; 181(4): 655-666 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Hironori Kawahara, Takao Imai, Hiroaki Imataka, Masafumi Tsujimoto, Ken Matsumoto, and Hideyuki Okano
Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP
JCB 2008; 181(4): 639-653 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Meng Xu and Peter R. Cook
Similar active genes cluster in specialized transcription factories
JCB 2008; 181(4): 615-623 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Amanda E. Bass-Zubek, Ryan P. Hobbs, Evangeline V. Amargo, Nicholas J. Garcia, Sherry N. Hsieh, Xinyu Chen, James K. Wahl III, Mitchell F. Denning, and Kathleen J. Green
Plakophilin 2: a critical scaffold for PKC{alpha} that regulates intercellular junction assembly
JCB 2008; 181(4): 605-613 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Thomas M. Durcan, Elizabeth S. Halpin, Trisha Rao, Nicholas S. Collins, Emily K. Tribble, Jessica E. Hornick, and Edward H. Hinchcliffe
Tektin 2 is required for central spindle microtubule organization and the completion of cytokinesis
JCB 2008; 181(4): 595-603 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Ajit P. Joglekar, David Bouck, Ken Finley, Xingkun Liu, Yakun Wan, Judith Berman, Xiangwei He, E.D. Salmon, and Kerry S. Bloom
Molecular architecture of the kinetochore-microtubule attachment site is conserved between point and regional centromeres
JCB 2008; 181(4): 587-594 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Robin White, Constantin Gonsior, Eva-Maria Krämer-Albers, Nadine Stöhr, Stefan Hüttelmaier, and Jacqueline Trotter
Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2–dependent RNA granules
JCB 2008; 181(4): 579-586 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Houman Khosravani, Yunfeng Zhang, Shigeki Tsutsui, Shahid Hameed, Christophe Altier, Jawed Hamid, Lina Chen, Michelle Villemaire, Zenobia Ali, Frank R. Jirik, and Gerald W. Zamponi
Prion protein attenuates excitotoxicity by inhibiting NMDA receptors
JCB 2008; 181(3): 551-565 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Naoto Kakinuma, Badal Chandra Roy, Yun Zhu, Yong Wang, and Ryoiti Kiyama
Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K–Akt signaling
JCB 2008; 181(3): 537-549 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Francesca Bartolini, James B. Moseley, Jan Schmoranzer, Lynne Cassimeris, Bruce L. Goode, and Gregg G. Gundersen
The formin mDia2 stabilizes microtubules independently of its actin nucleation activity
JCB 2008; 181(3): 523-536 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Melissa L. Hancock, Sarah E. Canetta, Lorna W. Role, and David A. Talmage
Presynaptic Type III Neuregulin1-ErbB signaling targets {alpha}7 nicotinic acetylcholine receptors to axons
JCB 2008; 181(3): 511-521 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Taichi Hara, Akito Takamura, Chieko Kishi, Shun-ichiro Iemura, Tohru Natsume, Jun-Lin Guan, and Noboru Mizushima
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
JCB 2008; 181(3): 497-510 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

David Michaelson, Wasif Abidi, Daniele Guardavaccaro, Mo Zhou, Ian Ahearn, Michele Pagano, and Mark R. Philips
Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division
JCB 2008; 181(3): 485-496 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Jun Wu, Hyekyung P. Cho, David B. Rhee, Dabney K. Johnson, John Dunlap, Yie Liu, and Yisong Wang
Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication
JCB 2008; 181(3): 475-483 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Yueting Shang, Tadashi Yoshida, Brad A. Amendt, James F. Martin, and Gary K. Owens
Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation
JCB 2008; 181(3): 461-473 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Sahn-ho Kim, Albert R. Davalos, Seok-Jin Heo, Francis Rodier, Ying Zou, Christian Beausejour, Patrick Kaminker, Steven M. Yannone, and Judith Campisi
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
JCB 2008; 181(3): 447-460 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Yan-Qing Ma, Jun Qin, Chuanyue Wu, and Edward F. Plow
Kindlin-2 (Mig-2): a co-activator of β3 integrins
JCB 2008; 181(3): 439-446 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Christopher L. de Graffenried, Helen H. Ho, and Graham Warren
Polo-like kinase is required for Golgi and bilobe biogenesis in Trypanosoma brucei
JCB 2008; 181(3): 431-438 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Gohta Goshima, Mirjam Mayer, Nan Zhang, Nico Stuurman, and Ronald D. Vale
Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle
JCB 2008; 181(3): 421-429 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Yumi Kim, John E. Heuser, Clare M. Waterman, and Don W. Cleveland
CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether
JCB 2008; 181(3): 411-419 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jason J. Zoeller, Angela McQuillan, John Whitelock, Shiu-Ying Ho, and Renato V. Iozzo
A central function for perlecan in skeletal muscle and cardiovascular development
JCB 2008; 181(2): 381-394 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Junji Yamauchi, Yuki Miyamoto, Jonah R. Chan, and Akito Tanoue
ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration
JCB 2008; 181(2): 351-365 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Youssef H. Zeidan, Russell W. Jenkins, and Yusuf A. Hannun
Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway
JCB 2008; 181(2): 335-350 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Juying Li, Helen L. Yin, and Junying Yuan
Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity
JCB 2008; 181(2): 321-333 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Bradley R. Pearse, Luke Gabriel, Ning Wang, and Daniel N. Hebert
A cell-based reglucosylation assay demonstrates the role of GT1 in the quality control of a maturing glycoprotein
JCB 2008; 181(2): 309-320 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Francisco Ramírez-Valle, Steve Braunstein, Jiri Zavadil, Silvia C. Formenti, and Robert J. Schneider
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy
JCB 2008; 181(2): 293-307 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Ramsey A. Saleem, Barbara Knoblach, Fred D. Mast, Jennifer J. Smith, John Boyle, C. Melissa Dobson, Rose Long-O'Donnell, Richard A. Rachubinski, and John D. Aitchison
Genome-wide analysis of signaling networks regulating fatty acid–induced gene expression and organelle biogenesis
JCB 2008; 181(2): 281-292 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Dale K. Shumaker, Liliana Solimando, Kaushik Sengupta, Takeshi Shimi, Stephen A. Adam, Antje Grunwald, Sergei V. Strelkov, Ueli Aebi, M. Cristina Cardoso, and Robert D. Goldman
The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication
JCB 2008; 181(2): 269-280 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Michael J. Emanuele, Weijie Lan, Miri Jwa, Stephanie A. Miller, Clarence S.M. Chan, and P. Todd Stukenberg
Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly
JCB 2008; 181(2): 241-254 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Christoph Spycher, Edward S. Miller, Kelly Townsend, Lucijana Pavic, Nicholas A. Morrice, Pavel Janscak, Grant S. Stewart, and Manuel Stucki
Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin
JCB 2008; 181(2): 227-240 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Fredrik Melander, Simon Bekker-Jensen, Jacob Falck, Jiri Bartek, Niels Mailand, and Jiri Lukas
Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin
JCB 2008; 181(2): 213-226 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Ona Bloom, Julia J. Unternaehrer, Aimin Jiang, Jeong-Sook Shin, Lélia Delamarre, Patrick Allen, and Ira Mellman
Spinophilin participates in information transfer at immunological synapses
JCB 2008; 181(2): 203-211 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Chi-Kuo Hu, Margaret Coughlin, Christine M. Field, and Timothy J. Mitchison
Cell polarization during monopolar cytokinesis
JCB 2008; 181(2): 195-202 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Cindy V. Ly, Chi-Kuang Yao, Patrik Verstreken, Tomoko Ohyama, and Hugo J. Bellen
straightjacket is required for the synaptic stabilization of cacophony, a voltage-gated calcium channel {alpha}1 subunit
JCB 2008; 181(1): 157-170 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jacqueline Fernandes, Ivan M. Lorenzo, Yaniré N. Andrade, Anna Garcia-Elias, Selma A. Serra, José M. Fernández-Fernández, and Miguel A. Valverde
IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid
JCB 2008; 181(1): 143-155 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Kyoko Kawasaki, Tetsuro Watabe, Hitoshi Sase, Masanori Hirashima, Hiroshi Koide, Yasuyuki Morishita, Keiko Yuki, Toshikuni Sasaoka, Toshio Suda, Motoya Katsuki, Kohei Miyazono, and Keiji Miyazawa
Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells
JCB 2008; 181(1): 131-141 [Abstract] [Full Text]  
Article supplement(s): [ Supplemental Material Index]

Katrin Altmann, Martina Frank, Daniel Neumann, Stefan Jakobs, and Benedikt Westermann
The class V myosin motor protein, Myo2, plays a major role in mitochondrial motility in Saccharomyces cerevisiae
JCB 2008; 181(1): 119-130 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Paolo Ronchi, Sara Colombo, Maura Francolini, and Nica Borgese
Transmembrane domain–dependent partitioning of membrane proteins within the endoplasmic reticulum
JCB 2008; 181(1): 105-118 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Dawn M. Clifford, Benjamin A. Wolfe, Rachel H. Roberts-Galbraith, W. Hayes McDonald, John R. Yates III, and Kathleen L. Gould
The Clp1/Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1
JCB 2008; 181(1): 79-88 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Biljana Culjkovic, Keith Tan, Slobodanka Orolicki, Abdellatif Amri, Sylvain Meloche, and Katherine L.B. Borden
The eIF4E RNA regulon promotes the Akt signaling pathway
JCB 2008; 181(1): 51-63 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Sara M. Weis, Ssang-Taek Lim, Kimberly M. Lutu-Fuga, Leo A. Barnes, Xiao Lei Chen, Joachim R. Göthert, Tang-Long Shen, Jun-Lin Guan, David D. Schlaepfer, and David A. Cheresh
Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK
JCB 2008; 181(1): 43-50 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jesús Espada, Ignacio Varela, Ignacio Flores, Alejandro P. Ugalde, Juan Cadiñanos, Alberto M. Pendás, Colin L. Stewart, Karl Tryggvason, María A. Blasco, José M.P. Freije, and Carlos López-Otín
Nuclear envelope defects cause stem cell dysfunction in premature-aging mice
JCB 2008; 181(1): 27-35 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Related biobytes podcast]

Yasushi Shintani, Yuri Fukumoto, Nina Chaika, Robert Svoboda, Margaret J. Wheelock, and Keith R. Johnson
Collagen I–mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1
JCB 2008; 180(6): 1277-1289 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jacky G. Goetz, Bharat Joshi, Patrick Lajoie, Scott S. Strugnell, Trevor Scudamore, Liliana D. Kojic, and Ivan R. Nabi
Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1
JCB 2008; 180(6): 1261-1275 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Corina Sarmiento, Weigang Wang, Athanassios Dovas, Hideki Yamaguchi, Mazen Sidani, Mirvat El-Sibai, Vera DesMarais, Holly A. Holman, Susan Kitchen, Jonathan M. Backer, Art Alberts, and John Condeelis
WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells
JCB 2008; 180(6): 1245-1260 [Abstract] [Full Text]  
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Maria Nemethova, Sonja Auinger, and J. Victor Small
Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella
JCB 2008; 180(6): 1233-1244 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Fatima-Zahra Idrissi, Helga Grötsch, Isabel M. Fernández-Golbano, Cristina Presciatto-Baschong, Howard Riezman, and María-Isabel Geli
Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membrane
JCB 2008; 180(6): 1219-1232 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Ruth I. Johnson, Midori J. Seppa, and Ross L. Cagan
The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning
JCB 2008; 180(6): 1191-1204 [Abstract] [Full Text]  
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Jianjun Wang, Chuan-En Wang, Adam Orr, Suzanne Tydlacka, Shi-Hua Li, and Xiao-Jiang Li
Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice
JCB 2008; 180(6): 1177-1189 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Ying Jiang, Zhiliang Cheng, Elisabet C. Mandon, and Reid Gilmore
An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation
JCB 2008; 180(6): 1149-1161 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Kazuhito Toyo-oka, Daisuke Mori, Yoshihisa Yano, Masayuki Shiota, Hiroshi Iwao, Hidemasa Goto, Masaki Inagaki, Noriko Hiraiwa, Masami Muramatsu, Anthony Wynshaw-Boris, Atsushi Yoshiki, and Shinji Hirotsune
Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation
JCB 2008; 180(6): 1133-1147 [Abstract] [Full Text]  
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Norihiko Nakazawa, Takahiro Nakamura, Aya Kokubu, Masahiro Ebe, Koji Nagao, and Mitsuhiro Yanagida
Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis
JCB 2008; 180(6): 1115-1131 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Peter Hemmerich, Stefanie Weidtkamp-Peters, Christian Hoischen, Lars Schmiedeberg, Indri Erliandri, and Stephan Diekmann
Dynamics of inner kinetochore assembly and maintenance in living cells
JCB 2008; 180(6): 1101-1114 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Xiao-qing Gan, Ji-yong Wang, Ying Xi, Zhi-li Wu, Yi-ping Li, and Lin Li
Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabiLization of β-catenin–TCF interaction
JCB 2008; 180(6): 1087-1100 [Abstract] [Full Text]  
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Julie M. Caldwell, Yinhuai Chen, Kaila L. Schollaert, James F. Theis, George F. Babcock, Carol S. Newlon, and Yolanda Sanchez
Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins
JCB 2008; 180(6): 1073-1086 [Abstract] [Full Text]  
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Ioannis P. Nezis, Anne Simonsen, Antonia P. Sagona, Kim Finley, Sébastien Gaumer, Didier Contamine, Tor Erik Rusten, Harald Stenmark, and Andreas Brech
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
JCB 2008; 180(6): 1065-1071 [Abstract] [Full Text]  
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Hao-Ven Wang, Ling-Wei Chang, Klara Brixius, Sara A. Wickström, Eloi Montanez, Ingo Thievessen, Martin Schwander, Ulrich Müller, Wilhelm Bloch, Ulrike Mayer, and Reinhard Fässler
Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage
JCB 2008; 180(5): 1037-1049 [Abstract] [Full Text]  
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Grzegorz M. Wilczynski, Filip A. Konopacki, Ewa Wilczek, Zofia Lasiecka, Adam Gorlewicz, Piotr Michaluk, Marcin Wawrzyniak, Monika Malinowska, Pawel Okulski, Lukasz R. Kolodziej, Witold Konopka, Kamila Duniec, Barbara Mioduszewska, Evgeni Nikolaev, Agnieszka Walczak, Dorota Owczarek, Dariusz C. Gorecki, Werner Zuschratter, Ole Petter Ottersen, and Leszek Kaczmarek
Important role of matrix metalloproteinase 9 in epileptogenesis
JCB 2008; 180(5): 1021-1035 [Abstract] [Full Text]  
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Kostandin V. Pajcini, Jason H. Pomerantz, Ozan Alkan, Regis Doyonnas, and Helen M. Blau
Myoblasts and macrophages share molecular components that contribute to cell–cell fusion
JCB 2008; 180(5): 1005-1019 [Abstract] [Full Text]  
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Richard K. Tsai and Dennis E. Discher
Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells
JCB 2008; 180(5): 989-1003 [Abstract] [Full Text]  
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Andrew R. Jauregui, Ken C.Q. Nguyen, David H. Hall, and Maureen M. Barr
The Caenorhabditis elegans nephrocystins act as global modifiers of cilium structure
JCB 2008; 180(5): 973-988 [Abstract] [Full Text]  
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Christa L. Cortesio, Keefe T. Chan, Benjamin J. Perrin, Nicholas O. Burton, Sheng Zhang, Zhong-Yin Zhang, and Anna Huttenlocher
Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion
JCB 2008; 180(5): 957-971 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Gergana Galabova-Kovacs, Federica Catalanotti, Dana Matzen, Gloria X. Reyes, Jürgen Zezula, Ruth Herbst, Alcino Silva, Ingrid Walter, and Manuela Baccarini
Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development
JCB 2008; 180(5): 947-955 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Gayatri Pal, Maria T.Z. Paraz, and Douglas R. Kellogg
Regulation of Mih1/Cdc25 by protein phosphatase 2A and casein kinase 1
JCB 2008; 180(5): 931-945 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Ruwin Pandithage, Richard Lilischkis, Kai Harting, Alexandra Wolf, Britta Jedamzik, Juliane Lüscher-Firzlaff, Jörg Vervoorts, Edwin Lasonder, Elisabeth Kremmer, Bernd Knöll, and Bernhard Lüscher
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility
JCB 2008; 180(5): 915-929 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Vincent Idone, Christina Tam, John W. Goss, Derek Toomre, Marc Pypaert, and Norma W. Andrews
Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis
JCB 2008; 180(5): 905-914 [Abstract] [Full Text]  
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Enko N. Kiprilov, Aashir Awan, Romain Desprat, Michelle Velho, Christian A. Clement, Anne Grete Byskov, Claus Y. Andersen, Peter Satir, Eric E. Bouhassira, Søren T. Christensen, and Rhoda Elison Hirsch
Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery
JCB 2008; 180(5): 897-904 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Isabelle Rouiller, Xiao-Ping Xu, Kurt J. Amann, Coumaran Egile, Stephan Nickell, Daniela Nicastro, Rong Li, Thomas D. Pollard, Niels Volkmann, and Dorit Hanein
The structural basis of actin filament branching by the Arp2/3 complex
JCB 2008; 180(5): 887-895 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

David M. Rivers, Sergio Moreno, Mary Abraham, and Julie Ahringer
PAR proteins direct asymmetry of the cell cycle regulators Polo-like kinase and Cdc25
JCB 2008; 180(5): 877-885 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Hideki Yokoyama, Oliver J. Gruss, Sofia Rybina, Maïwen Caudron, Malgorzata Schelder, Matthias Wilm, Iain W. Mattaj, and Eric Karsenti
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
JCB 2008; 180(5): 867-875 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Elisa Dultz, Esther Zanin, Claudia Wurzenberger, Marion Braun, Gwénaël Rabut, Lucia Sironi, and Jan Ellenberg
Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells
JCB 2008; 180(5): 857-865 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Chan Choo Yap, Dolora Wisco, Pekka Kujala, Zofia M. Lasiecka, Johanna T. Cannon, Michael C. Chang, Harald Hirling, Judith Klumperman, and Bettina Winckler
The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM
JCB 2008; 180(4): 827-842 [Abstract] [Full Text]  
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Hui Jin, J. Michael McCaffery, and Eric Grote
Ergosterol promotes pheromone signaling and plasma membrane fusion in mating yeast
JCB 2008; 180(4): 813-826 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Anastasia Blagoveshchenskaya, Fei Ying Cheong, Holger M. Rohde, Greta Glover, Andreas Knödler, Teresa Nicolson, Guido Boehmelt, and Peter Mayinger
Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1
JCB 2008; 180(4): 803-812 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Nadine Bakkar, Jingxin Wang, Katherine J. Ladner, Huating Wang, Jason M. Dahlman, Micheal Carathers, Swarnali Acharyya, Michael A. Rudnicki, Andrew D. Hollenbach, and Denis C. Guttridge
IKK/NF-{kappa}B regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
JCB 2008; 180(4): 787-802 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Alexander Dammermann, Paul S. Maddox, Arshad Desai, and Karen Oegema
SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the {gamma}-tubulin–mediated addition of centriolar microtubules
JCB 2008; 180(4): 771-785 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Miki Hieda, Mayumi Isokane, Michiko Koizumi, Chiduru Higashi, Taro Tachibana, Masachika Shudou, Tomohiko Taguchi, Yohki Hieda, and Shigeki Higashiyama
Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane
JCB 2008; 180(4): 763-769 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Thomas Vaccari, Han Lu, Ritu Kanwar, Mark E. Fortini, and David Bilder
Endosomal entry regulates Notch receptor activation in Drosophila melanogaster
JCB 2008; 180(4): 755-762 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Douwe M. Veltman, Ineke Keizer-Gunnik, and Peter J.M. Van Haastert
Four key signaling pathways mediating chemotaxis in Dictyostelium discoideum
JCB 2008; 180(4): 747-753 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Sébastien Carreno, Ilektra Kouranti, Edith Szafer Glusman, Margaret T. Fuller, Arnaud Echard, and François Payre
Moesin and its activating kinase Slik are required for cortical stability and microtubule organization in mitotic cells
JCB 2008; 180(4): 739-746 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Katharina A. Dragestein, Wiggert A. van Cappellen, Jeffrey van Haren, George D. Tsibidis, Anna Akhmanova, Tobias A. Knoch, Frank Grosveld, and Niels Galjart
Dynamic behavior of GFP–CLIP-170 reveals fast protein turnover on microtubule plus ends
JCB 2008; 180(4): 729-737 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Liwei Wang, Zhouhua Li, and Yu Cai
The JAK/STAT pathway positively regulates DPP signaling in the Drosophila germline stem cell niche
JCB 2008; 180(4): 721-728 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Auxiliadora Aguilera-Romero, Joanna Kaminska, Anne Spang, Howard Riezman, and Manuel Muñiz
The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus
JCB 2008; 180(4): 713-720 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Beat Nyfeler, Veronika Reiterer, Markus W. Wendeler, Eduard Stefan, Bin Zhang, Stephen W. Michnick, and Hans-Peter Hauri
Identification of ERGIC-53 as an intracellular transport receptor of {alpha}1-antitrypsin
JCB 2008; 180(4): 705-712 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Min Chen, Lena Singer, Andrea Scharf, and Anna von Mikecz
Nuclear polyglutamine-containing protein aggregates as active proteolytic centers
JCB 2008; 180(4): 697-704 [Abstract] [Full Text]  
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Kieran F. Harvey, Jaakko Mattila, Avi Sofer, F. Christian Bennett, Matthew R. Ramsey, Leif W. Ellisen, Oscar Puig, and Iswar K. Hariharan
FOXO-regulated transcription restricts overgrowth of Tsc mutant organs
JCB 2008; 180(4): 691-696 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Andrew B. Fielding, Iveta Dobreva, Paul C. McDonald, Leonard J. Foster, and Shoukat Dedhar
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization
JCB 2008; 180(4): 681-689 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Fang Yang, Sigrid Eckardt, N. Adrian Leu, K. John McLaughlin, and Peijing Jeremy Wang
Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis
JCB 2008; 180(4): 673-679 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Sarah L. Thompson and Duane A. Compton
Examining the link between chromosomal instability and aneuploidy in human cells
JCB 2008; 180(4): 665-672 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Nicole LeBrasseur and Ruth Williams
Capital Cells: The American Society for Cell Biology, Washington, D.C., December 1–5, 2007
JCB 2008; 180(4): 654-659 [Full Text]  
Article supplement(s): [biobytes podcast]

Karl-Ferdinand Lechtreck, Philippe Delmotte, Michael L. Robinson, Michael J. Sanderson, and George B. Witman
Mutations in Hydin impair ciliary motility in mice
JCB 2008; 180(3): 633-643 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Harald Witte, Dorothee Neukirchen, and Frank Bradke
Microtubule stabilization specifies initial neuronal polarization
JCB 2008; 180(3): 619-632 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Raz Ben-Yair and Chaya Kalcheim
Notch and bone morphogenetic protein differentially act on dermomyotome cells to generate endothelium, smooth, and striated muscle
JCB 2008; 180(3): 607-618 [Abstract] [Full Text]  
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Daniela D'Andrea, Giovanna L. Liguori, J. Ann Le Good, Enza Lonardo, Olov Andersson, Daniel B. Constam, Maria G. Persico, and Gabriella Minchiotti
Cripto promotes A–P axis specification independently of its stimulatory effect on Nodal autoinduction
JCB 2008; 180(3): 597-605 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Séverine Boulon, Nathalie Marmier-Gourrier, Bérengère Pradet-Balade, Laurence Wurth, Céline Verheggen, Beáta E. Jády, Benjamin Rothé, Christina Pescia, Marie-Cécile Robert, Tamás Kiss, Barbara Bardoni, Alain Krol, Christiane Branlant, Christine Allmang, Edouard Bertrand, and Bruno Charpentier
The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery
JCB 2008; 180(3): 579-595 [Abstract] [Full Text]  
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Rongmin Zhao, Yoshito Kakihara, Anna Gribun, Jennifer Huen, Guocheng Yang, May Khanna, Michael Costanzo, Renée L. Brost, Charles Boone, Timothy R. Hughes, Christopher M. Yip, and Walid A. Houry
Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation
JCB 2008; 180(3): 563-578 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Edward M. Campbell, Omar Perez, Jenny L. Anderson, and Thomas J. Hope
Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5{alpha}
JCB 2008; 180(3): 549-561 [Abstract] [Full Text]  
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Graham J. Buttrick, Luke M.A. Beaumont, Jessica Leitch, Christopher Yau, Julian R. Hughes, and James G. Wakefield
Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo
JCB 2008; 180(3): 537-548 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Shan Gao, Maria Grazia Giansanti, Graham J. Buttrick, Sharada Ramasubramanyan, Adam Auton, Maurizio Gatti, and James G. Wakefield
Australin: a chromosomal passenger protein required specifically for Drosophila melanogaster male meiosis
JCB 2008; 180(3): 521-535 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jakub K. Famulski, Larissa Vos, Xuejun Sun, and Gordon Chan
Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint
JCB 2008; 180(3): 507-520 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Kiyoshi Tahara, Masatoshi Takagi, Miho Ohsugi, Takefumi Sone, Fumiko Nishiumi, Kazuhiro Maeshima, Yasuomi Horiuchi, Noriko Tokai-Nishizumi, Fumio Imamoto, Tadashi Yamamoto, Shingo Kose, and Naoko Imamoto
Importin-β and the small guanosine triphosphatase Ran mediate chromosome loading of the human chromokinesin Kid
JCB 2008; 180(3): 493-506 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Weihua Fei, Guanghou Shui, Bruno Gaeta, Ximing Du, Lars Kuerschner, Peng Li, Andrew J. Brown, Markus R. Wenk, Robert G. Parton, and Hongyuan Yang
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast
JCB 2008; 180(3): 473-482 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Jianwei Zou, Mark A. Hallen, Christine D. Yankel, and Sharyn A. Endow
A microtubule-destabilizing kinesin motor regulates spindle length and anchoring in oocytes
JCB 2008; 180(3): 459-466 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Angélique Millon-Frémillon, Daniel Bouvard, Alexei Grichine, Sandra Manet-Dupé, Marc R. Block, and Corinne Albiges-Rizo
Cell adaptive response to extracellular matrix density is controlled by ICAP-1–dependent β1-integrin affinity
JCB 2008; 180(2): 427-441 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Chun Yang, Heather A. Owen, and Pinfen Yang
Dimeric heat shock protein 40 binds radial spokes for generating coupled power strokes and recovery strokes of 9 + 2 flagella
JCB 2008; 180(2): 403-415 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Dumaine Williams and Jeffrey E. Pessin
Mapping of R-SNARE function at distinct intracellular GLUT4 trafficking steps in adipocytes
JCB 2008; 180(2): 375-387 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Paolo M. Mangahas, Xiaomeng Yu, Kenneth G. Miller, and Zheng Zhou
The small GTPase Rab2 functions in the removal of apoptotic cells in Caenorhabditis elegans
JCB 2008; 180(2): 357-373 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Erinna F. Lee, Peter E. Czabotar, Mark F. van Delft, Ewa M. Michalak, Michelle J. Boyle, Simon N. Willis, Hamsa Puthalakath, Philippe Bouillet, Peter M. Colman, David C.S. Huang, and W. Douglas Fairlie
A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation
JCB 2008; 180(2): 341-355 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Fangfang Liu, Seng Kah Ng, Yanfen Lu, Wilson Low, Julian Lai, and Gregory Jedd
Making two organelles from one: Woronin body biogenesis by peroxisomal protein sorting
JCB 2008; 180(2): 325-339 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Kieran Ritchie, Claudia Seah, Jana Moulin, Christian Isaac, Frederick Dick, and Nathalie G. Bérubé
Loss of ATRX leads to chromosome cohesion and congression defects
JCB 2008; 180(2): 315-324 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Livia Maria Pirzio, Pietro Pichierri, Margherita Bignami, and Annapaola Franchitto
Werner syndrome helicase activity is essential in maintaining fragile site stability
JCB 2008; 180(2): 305-314 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Elias T. Spiliotis, Stephen J. Hunt, Qicong Hu, Makoto Kinoshita, and W. James Nelson
Epithelial polarity requires septin coupling of vesicle transport to polyglutamylated microtubules
JCB 2008; 180(2): 295-303 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Gilles R.X. Hickson and Patrick H. O'Farrell
Rho-dependent control of anillin behavior during cytokinesis
JCB 2008; 180(2): 285-294 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Xuelin Wang, Wei Zhang, Thomas Cheever, Valentin Schwarz, Karla Opperman, Harald Hutter, Deanna Koepp, and Lihsia Chen
The C. elegans L1CAM homologue LAD-2 functions as a coreceptor in MAB-20/Sema2–mediated axon guidance
JCB 2008; 180(1): 233-246 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index] [Supplemental Material Index]

Chunyue Yin, Maria Kiskowski, Philippe-Alexandre Pouille, Emmanuel Farge, and Lilianna Solnica-Krezel
Cooperation of polarized cell intercalations drives convergence and extension of presomitic mesoderm during zebrafish gastrulation
JCB 2008; 180(1): 221-232 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Peter M. Benz, Constanze Blume, Jan Moebius, Chris Oschatz, Kai Schuh, Albert Sickmann, Ulrich Walter, Stephan M. Feller, and Thomas Renné
Cytoskeleton assembly at endothelial cell–cell contacts is regulated by {alpha}II-spectrin–VASP complexes
JCB 2008; 180(1): 205-219 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

Yangmi Lim, Ssang-Taek Lim, Alok Tomar, Margaret Gardel, Joie A. Bernard-Trifilo, Xiao Lei Chen, Sean A. Uryu, Rafaela Canete-Soler, Jinbin Zhai, Hong Lin, William W. Schlaepfer, Perihan Nalbant, Gary Bokoch, Dusko Ilic, Clare Waterman-Storer, and David D. Schlaepfer
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility
JCB 2008; 180(1): 187-203 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Material Index]

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Article supplement(s): [Supplemental Material Index]